Evidence map›Paper›PMID 32474657›Full record

ArticleJournal of neurology2020

COVID-19-associated acute disseminated encephalomyelitis (ADEM).

Timothy Parsons, Sarah Banks, Chay Bae, Joel Gelber, Hussein Alahmadi, Matthew Tichauer

Open access · bronzeAbstract readCase ReportsLetter
In one paragraph

Article in Journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 15 pooled it
32.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 15 syntheses or guidelines pooled it, 232 citations in OpenAlex.

  1. Neurological and Head/Eyes/Ears/Nose/Throat Manifestations of COVID-19: A Systematic Review and Meta-Analysis.The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2022
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. COVID-19 associated brain/spinal cord lesions and leptomeningeal enhancement: A meta-analysis of the relationship to CSF SARS-CoV-2.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2021
    Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Neurological manifestations of COVID-19: a systematic review and meta-analysis of proportions.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Pooled it
  14. Pooled it
  15. Pooled it
  16. Article
  17. Article
  18. Article
  19. Article
  20. The neurobiology of SARS-CoV-2 infection.Nature reviews. Neuroscience · 2024
    Review

79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Timothy ParsonsThe Hospital of Central Connecticut, Hartford Healthcare, 100 Grand St., New Britain, CT, 06052, USA. timothy.parsons@hhchealth.org.ORCID http://orcid.org/0000-0001-9088-1929
Sarah BanksThe Hospital of Central Connecticut, Hartford Healthcare, 100 Grand St., New Britain, CT, 06052, USA.
Chay BaeUniversity of Connecticut School of Medicine, Farmington, CT, USA.
Joel GelberThe Hospital of Central Connecticut, Hartford Healthcare, 100 Grand St., New Britain, CT, 06052, USA.
Hussein AlahmadiThe Hospital of Central Connecticut, Hartford Healthcare, 100 Grand St., New Britain, CT, 06052, USA.
Matthew TichauerThe Hospital of Central Connecticut, Hartford Healthcare, 100 Grand St., New Britain, CT, 06052, USA.
The Hospital of Central Connecticut · USUniversity of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 51-year-old woman with COVID-19 infection developed coma and an impaired oculocephalic response to one side. MRI of the brain demonstrated acute multifocal demyelinating lesions, and CSF testing did not identify a direct cerebral infection. High-dose steroids followed by a course of IVIG was administered, and the patient regained consciousness over the course of several weeks. As more patients reach the weeks after initial infection with COVID-19, acute disseminated encephalomyelitis should be considered a potentially treatable cause of profound encephalopathy or multifocal neurological deficits.

Indexed as

Anti-Inflammatory AgentsBetacoronavirusCoronavirus InfectionsCOVID-19Encephalomyelitis, Acute DisseminatedFemaleHumansImmunoglobulins, IntravenousMethylprednisoloneMiddle AgedPandemicsPneumonia, ViralSARS-CoV-2Anti-Inflammatory AgentsImmunoglobulins, IntravenousMethylprednisoloneADEMCoronavirusCOVID-19Demyelinating diseasePost-infectious

Identifiers

PMID32474657
PMCPMC7260459
OpenAlexW3028809942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.