Evidence map›Paper›PMID 32474010›Full record

ReviewTrends in microbiology2020

Fungal Pathogens: Shape-Shifting Invaders.

Kyunghun Min, Aaron M Neiman, James B Konopka

Open access · greenAbstract readReview
In one paragraph

Review in Trends in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
0.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. UnderstandingJournal of medical microbiology · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. DecipheringMicrobiology spectrum · 2025
    Article
  11. Review
  12. A Rare Case of Keratitis Caused byInfection and drug resistance · 2025
    Article
  13. Regulation of yeast polarized exocytosis by phosphoinositide lipids.Cellular and molecular life sciences : CMLS · 2024
    Review
  14. Phenotypic characterization ofMicrobiology spectrum · 2024
    Article
  15. Sur7 mediates a novel pathway for PIMolecular biology of the cell · 2024
    Article
  16. Article
  17. Phenotypic characterization ofbioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kyunghun MinDepartment of Microbiology and Immunology, Stony Brook University, Stony Brook, NY, USA.
Aaron M NeimanDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, USA.
James B KonopkaDepartment of Microbiology and Immunology, Stony Brook University, Stony Brook, NY, USA. Electronic address: james.konopka@stonybrook.edu.
Stony Brook University · US

Funding

Regulation of Morphogenesis in C. albicansR01AI047837 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI James B Konopka · 2001 to 2026
$8.8M
Equipment supplement for grant R01 GM072540 Assembly and Function of the Yeast Spore Wall.R01GM072540 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI NEIMAN, AARON M · 2005 to 2025
$7.1M
Signal pathways controlling the bud to hypha transitionR01GM116048 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI KONOPKA, JAMES B · 2015 to 2022
$2.5M
NIAID NIH HHS R01 AI047837NIGMS NIH HHS R01 GM072540NIGMS NIH HHS R01 GM116048
6 · The paper itself

Abstract

Fungal infections are on the rise due to new medical procedures that have increased the number of immune compromised patients, antibacterial antibiotics that disrupt the microbiome, and increased use of indwelling medical devices that provide sites for biofilm formation. Key to understanding the mechanisms of pathogenesis is to determine how fungal morphology impacts virulence strategies. For example, small budding cells use very different strategies to disseminate compared with long hyphal filaments. Furthermore, cell morphology must be monitored in the host, as many fungal pathogens change their shape to disseminate into new areas, acquire nutrients, and avoid attack by the immune system. This review describes the shape-shifting alterations in morphogenesis of human fungal pathogens and how they influence virulence strategies.

Indexed as

AnimalsFungal ProteinsFungiGene Expression Regulation, FungalHumansHyphaeMycosesVirulenceFungal Proteinscapsuleconidiafungalhyphaemorphogenesispseudohyphaeyeast

Identifiers

PMID32474010
PMCPMC7572602
OpenAlexW3030215759

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.