Evidence map›Paper›PMID 32473625›Full record

ArticleBMC infectious diseases2020

Comparison of clinical features of acute lower respiratory tract infections in infants with RSV/HRV infection, and incidences of subsequent wheezing or asthma in childhood.

Qin Ding, Lili Xu, Yun Zhu, Baoping Xu, Xiangpeng Chen, Yali Duan, Zhengde Xie, Kunling Shen

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  8. [Asthma management and asthma control level in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Article
  9. Article
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  11. Article
  12. Review
  13. Treatment of Respiratory Viral Coinfections.Epidemiologia (Basel, Switzerland) · 2022
    Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Qin DingBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Lili XuBeijing Key Laboratory of Pediatric Respiratory Infection Diseases, Key Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics (Capital Medical University), Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Yun ZhuBeijing Key Laboratory of Pediatric Respiratory Infection Diseases, Key Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics (Capital Medical University), Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Baoping XuBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Xiangpeng ChenBeijing Key Laboratory of Pediatric Respiratory Infection Diseases, Key Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics (Capital Medical University), Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Yali DuanBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Zhengde XieBeijing Key Laboratory of Pediatric Respiratory Infection Diseases, Key Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics (Capital Medical University), Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China. xiezhengde@bch.com.cn.
Kunling ShenBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China. kunlingshen1717@163.com.
Capital Medical University · CNBeijing Children’s Hospital · CN

Funding

National Science and Technology Supported Projects 2013BAI09B11the National Science and Technology Major Projects for the Control and Prevention of Major Infectious Diseases in China 2017ZX10103004-004the National Science and Technology Major Projects for the Control and Prevention of Major Infectious Diseases in China 2017ZX10104001-005-010the National Science and Technology Major Projects for the Control and Prevention of Major Infectious Diseases in China 2018ZX10305409-001-004
6 · The paper itself

Abstract

backgroundTo compare the clinical characteristics of acute lower respiratory tract infections (ALRTIs) caused by respiratory syncytial virus (RSV) and human rhinovirus (HRV) and to explore the relationship between the development of recurrent wheezing/asthma and RSV/ HRV infections in infancy.

methodsRetrospective study was conducted to compare the clinical characteristics of acute lower respiratory tract infections (ALRTIs). Hospitalized patients with ALRTIs from March 2007 to December 2016 were screened. Single RSV cases (s-RSV), single HRV cases (s-HRV), and cases who had co-infection with the two viruses were enrolled. Follow-up was performed to determine whether either specific respiratory virus infection was related to subsequent development of recurrent wheezing/asthma.

resultsThe s-RSV children were the youngest (P = 0.021), they experienced the most serious condition (P < 0.001) and respiratory failure (P < 0.001), they also required highest demand of oxygen therapy (P < 0.001). And in s-RSV group, the incidence of development of recurrent wheezing was significantly higher in subgroup with the family history of wheezing than that without (P < 0.001).

conclusionThe s-RSV cases suffered from the worst severity of illness, respiratory failure and required highest demand of oxygen therapy. Recurrent wheezing was more common in s-RSV group with family history of wheezing than those without.

Indexed as

AsthmaChildChild, PreschoolCoinfectionFemaleHumansIncidenceInfantMalePicornaviridae InfectionsRespiratory SoundsRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsRetrospective StudiesAcute lower respiratory tract infectionAsthmaHuman rhinovirusRecurrent wheezingRespiratory syncytial virus

Identifiers

PMID32473625
PMCPMC7260463
OpenAlexW3030140774

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.