Evidence map›Paper›PMID 32473312›Full record

SynthesisTravel medicine and infectious disease

Efficacy of face mask in preventing respiratory virus transmission: A systematic review and meta-analysis.

Mingming Liang, Liang Gao, Ce Cheng, Qin Zhou, John Patrick Uy, Kurt Heiner, Chenyu Sun

Registry-linked trialOpen access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Travel medicine and infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05256082 (Impact of Face Masks on the Six Minute Walking Distance in Pulmonary Hypertension Patients During the COVID-19 Pandemic), which is not on this map. Cited by 216 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
216citing papers in PubMed, 15 pooled it
49.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05256082 nacompletednot on this map

Impact of Face Masks on the Six Minute Walking Distance in Pulmonary Hypertension Patients During the COVID-19 Pandemic: A Prospective, Randomized Cross-over Study

TypeinterventionalSponsorUniversity Hospital of CologneRan2020 to 2022Enrolled122ConditionsPulmonary HypertensionArmssix-minutes-walking test
3 · Its place in the literature

Who cites it

216 citing papers in PubMed, 15 syntheses or guidelines pooled it, 480 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Facemask use in community settings to prevent respiratory infection transmission: A rapid review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Pooled it
  14. Pooled it
  15. Pooled it
  16. Trial
  17. Trial
  18. Trial
  19. Article
  20. Article

156 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Mingming LiangDepartment of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, 230032, Anhui, PR China; Center for Evidence-Based Practice, Anhui Medical University, Hefei, 230032, Anhui, PR China.
Liang GaoCenter of Experimental Orthopaedics, Saarland University Medical Center, Kirrberger Straße Building 37-38, D-66421, Homburg, Saar, Germany.
Ce ChengDepartment of Internal Medicine, Cape Fear Valley Medical Center, Fayetteville, 28304, NC, USA.
Qin ZhouMayo Clinic, Rochester, MN, 55905, USA.
John Patrick UyAMITA Health Saint Joseph Hospital Chicago, Chicago, 60657, Illinois, USA.
Kurt HeinerDignity Health Mercy Hospital, Merced, 95340, CA, USA.
Chenyu SunAMITA Health Saint Joseph Hospital Chicago, Chicago, 60657, Illinois, USA. Electronic address: drsunchenyu@yeah.net.
Saint Joseph Hospital · USAnhui Medical University · CNCape Fear Valley Medical Center · USCooper Green Mercy Hospital · USMayo Clinic in Arizona · USSaarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConflicting recommendations exist related to whether masks have a protective effect on the spread of respiratory viruses.

methodsThe Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement was consulted to report this systematic review. Relevant articles were retrieved from PubMed, Web of Science, ScienceDirect, Cochrane Library, and Chinese National Knowledge Infrastructure (CNKI), VIP (Chinese) database.

resultsA total of 21 studies met our inclusion criteria. Meta-analyses suggest that mask use provided a significant protective effect (OR = 0.35 and 95% CI = 0.24-0.51). Use of masks by healthcare workers (HCWs) and non-healthcare workers (Non-HCWs) can reduce the risk of respiratory virus infection by 80% (OR = 0.20, 95% CI = 0.11-0.37) and 47% (OR = 0.53, 95% CI = 0.36-0.79). The protective effect of wearing masks in Asia (OR = 0.31) appeared to be higher than that of Western countries (OR = 0.45). Masks had a protective effect against influenza viruses (OR = 0.55), SARS (OR = 0.26), and SARS-CoV-2 (OR = 0.04). In the subgroups based on different study designs, protective effects of wearing mask were significant in cluster randomized trials and observational studies.

conclusionsThis study adds additional evidence of the enhanced protective value of masks, we stress that the use masks serve as an adjunctive method regarding the COVID-19 outbreak.

Indexed as

BetacoronavirusMasksCoronavirus InfectionsCOVID-19Disease Transmission, InfectiousHumansPandemicsPneumonia, ViralRespiratory Protective DevicesSARS-CoV-2FacemaskInfluenzaPreventionRespiratory virusSARS-CoVSARS-CoV-2

Identifiers

PMID32473312
PMCPMC7253999
OpenAlexW3030991920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.