Evidence map›Paper›PMID 32472982›Full record

ArticleBritish journal of health psychology2020

Primary care providers' use of and attitudes towards placebos: An exploratory focus group study with US physicians.

Michael H Bernstein, Cosima Locher, Sif Stewart-Ferrer, Sarah Buergler, Catherine M DesRoches, Michelle L Dossett, Franklin G Miller, Deborah Grose, Charlotte R Blease

Open access · bronzeAbstract read
In one paragraph

Article in British journal of health psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
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  7. Article
  8. Placebo: a brief updated review.Naunyn-Schmiedeberg's archives of pharmacology · 2022
    Review
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  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 6 countries.

Michael H BernsteinDepartment of Behavioral & Social Sciences, Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0001-7221-0697
Cosima LocherDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Sif Stewart-FerrerResearch Unit of General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-4350-0051
Sarah BuerglerDivision of Clinical Psychology & Psychotherapy, University of Basel, Switzerland.ORCID 0000-0002-5377-7505
Catherine M DesRochesGeneral Medicine and Primary Care Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Michelle L DossettDivision of General Internal Medicine and Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-0199-9675
Franklin G MillerDivision of Medical Ethics, Weill Cornell Medical College, New York, USA.
Deborah GroseProgram in Placebo Studies, Beth Isreal Deaconess Medical Center, Boston, Massachusetts, USA.
Charlotte R BleaseGeneral Medicine and Primary Care Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Beth Israel Deaconess Medical Center · USBoston Children's Hospital · USBrown University · USCornell University · USDeaconess Hospital · USMassachusetts General Hospital · USUniversity College Dublin · IEUniversity of Basel · CHUniversity of Southern Denmark · DK

Funding

Harnessing Placebo Analgesia to Address the Opioid EpidemicK01DA048087 · NIDA · RHODE ISLAND HOSPITAL · PI BERNSTEIN, MICHAEL HARRISON · 2019 to 2023
$903k
Improving Health Outcomes Through Enhanced Patient-Provider RelationshipsK23AT009218 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DOSSETT, MICHELLE L · 2016 to 2020
$801k
Foundation for the Science of the Therapeutic EncounterIrish Research CouncilNCCIH NIH HHS K23 AT009218NIDA NIH HHS K01 DA048087Swiss National Science Foundation P400PS_180730
6 · The paper itself

Abstract

objectiveTo examine how primary care physicians define placebo concepts, use placebos in clinical practice, and view open-label placebos (OLPs).

designSemi-structured focus groups that were audio-recorded and content-coded.

methodsTwo focus groups with a total of 15 primary care physicians occurred at medical centres in the New England region of the United States. Prior experience using placebo treatments and attitudes towards open-label placebos were explored. Themes were analysed using an inductive data-driven approach.

resultsPhysicians displayed a nuanced understanding of placebos and placebo effects in clinical contexts which sometimes focused on relational factors. Some respondents reported that they prescribed treatments with no known pharmacological effect for certain conditions and symptoms ('impure placebos') and that such prescriptions were more common for pain disorders, functional disorders, and medically unexplained symptoms. Opinions about OLP were mixed: Some viewed OLPs favourably or considered them 'harmless'; however, others strongly rejected OLPs as disrespectful to patients. Other issues in relation to OLPs included the following: lack of guidelines, legal and reputational concerns, and the notion that such treatments would run counter to customary medical practice.

conclusionsA number of physicians reported prescribing impure placebos in clinical care. Although some primary care physicians were resistant to the possibility of recommending OLPs, others regarded OLPs more favourably, viewing them as potential treatments, albeit with restricted potential. Statement of contribution What is already known? Many physicians report prescribing drugs for the purposes of eliciting a placebo effect. Initial evidence for the efficacy of open-label placebos is promising. What does this study add? A more nuanced description of the circumstances under which primary care physicians report placebo prescribing. A qualitative account of physician attitudes about using open-label placebos in clinical practice.

Indexed as

Attitude of Health PersonnelFemaleFocus GroupsHumansInterviews as TopicMaleMiddle AgedPhysiciansPlacebo EffectPlacebosPractice Patterns, Physicians'Primary Health CareUnited StatesPlacebosopen label placeboplaceboplacebo effectprimary care

Identifiers

PMID32472982
PMCPMC7423714
OpenAlexW3031084941

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.