Evidence map›Paper›PMID 32472656›Full record

ArticleBJS open2020

Impact of co-morbidities on health-related quality of life 10 years after surgical treatment of oesophageal cancer.

F Klevebro, A Johar, P Lagergren

Abstract read
In one paragraph

Article in BJS open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Nature, severity, and impact of chronic oropharyngeal dysphagia following curative resection for esophageal cancer: a cross-sectional study.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024
    Observational
  4. Article
  5. Article
  6. Health-related quality of life after esophagectomy in patients with esophageal cancer.Esophagus : official journal of the Japan Esophageal Society · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

F KlevebroSurgical Care Science, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0002-1695-4103
A JoharSurgical Care Science, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
P LagergrenSurgical Care Science, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0002-4634-0233

Funding

CancerfondenCancerföreningen i Stockholm
6 · The paper itself

Abstract

backgroundOesophagectomy for cancer is associated with long-term decreased health-related quality of life (HRQoL). The aim of this study was to evaluate the effect of co-morbidities on HRQoL among survivors of oesophageal or gastro-oesophageal junctional cancers after 10 years or more.

methodsThe study included a prospectively collected, population-based cohort, comprising all patients who had surgery for oesophageal or gastro-oesophageal junctional cancer in Sweden in 2001-2005 with follow-up until 31 December 2016. All data regarding patient and tumour characteristics, treatment details and HRQoL were collected using a prospectively created database. Multivariable ANCOVA regression models, adjusting for age, sex, tumour histology, stage and surgical technique, were used to calculate adjusted mean scores with 95 per cent confidence intervals for all HRQoL outcomes.

resultsA total of 92 survivors (88·5 per cent) responded to the questionnaires. Patients were stratified in two groups according to whether they reported a low or high impact of co-morbidities on general health. Patients in the high-impact group had clinically significantly decreased HRQoL and an increased level of symptoms, but differences between these two groups were not statistically significant.

conclusionCo-morbidities with high impact on general health still contribute to impaired HRQoL 10 years after oesophagectomy for cancer.

Indexed as

Quality of LifeAdultAgedAged, 80 and overComorbidityDatabases, FactualEsophageal NeoplasmsEsophagectomyEsophagogastric JunctionFemaleHumansMaleMiddle AgedMultivariate AnalysisProspective StudiesRegression Analysis

Identifiers

PMID32472656
PMCPMC7397362

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.