Evidence map›Paper›PMID 32472388›Full record

ArticlePharmacological reports : PR2020

The functional cooperation of 5-HT

Grzegorz Burnat, Piotr Brański, Joanna Solich, Magdalena Kolasa, Barbara Chruścicka, Marta Dziedzicka-Wasylewska, Andrzej Pilc

Open access · hybridAbstract read
In one paragraph

Article in Pharmacological reports : PR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Grzegorz BurnatDepartment of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343, Kraków, Poland. burnat@if-pan.krakow.pl.ORCID http://orcid.org/0000-0002-2300-0850
Piotr BrańskiDepartment of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343, Kraków, Poland.
Joanna SolichDepartment of Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343, Kraków, Poland.
Magdalena KolasaDepartment of Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343, Kraków, Poland.
Barbara ChruścickaDepartment of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343, Kraków, Poland.
Marta Dziedzicka-WasylewskaDepartment of Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343, Kraków, Poland.
Andrzej PilcDepartment of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343, Kraków, Poland. nfpilc@cyf-kr.edu.pl.
Maj Institute of Pharmacology · PLJagiellonian University · PL

Funding

Narodowe Centrum Nauki 2012/ 6/06/A/NZ7/00014 (MAESTRO)
6 · The paper itself

Abstract

backgroundThe serotonin 5-HT

methodsFirst, in vitro studies were performed to examine the pharmacological modulation of interaction of the mGlu4 and 5-HT

resultsThe ex vivo and in vitro results obtained in the present work suggest the existence of interactions between mGlu4 and 5-HT

conclusionThe existence of interactions between mGlu4 and 5-HT1A receptors may represent another signaling pathway involved in the development and treatment psychiatric disorders such as schizophrenia or depression.

Indexed as

AnimalsAntipsychotic AgentsBrainCell LineCyclic AMPHEK293 CellsHumansIn Situ Hybridization, FluorescenceMiceMice, Inbred C57BLReceptor, Serotonin, 5-HT1AReceptors, G-Protein-CoupledReceptors, Metabotropic GlutamateAntipsychotic AgentsCyclic AMPmetabotropic glutamate receptor 4Receptor, Serotonin, 5-HT1AReceptors, G-Protein-CoupledReceptors, Metabotropic Glutamate5-HT1A receptorsCell signalingCross-talkGpcrsmGlu4 receptors

Identifiers

PMID32472388
PMCPMC7550284
OpenAlexW3032592231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.