Evidence map›Paper›PMID 32472376›Full record

ReviewClinical journal of gastroenterology2020

Spur cell anemia related to alcoholic liver cirrhosis managed without liver transplantation: a case report and literature review.

Takao Miwa, Yuichiro Hatano, Takahiro Kochi, Masashi Aiba, Katsuhisa Toda, Hideko Goto, Noriaki Nakamura, Naoki Katsumura, Kenji Imai, Masahito Shimizu

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Clinical journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Spur Cell Anemia: Wolf in Disguise!Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. An Unusual Case of Hemolytic Anemia Reversed with Liver Transplantation.International journal of hematology-oncology and stem cell research · 2022
    Article
  7. Spur Cell Anaemia in Cirrhosis: A Narrative Review.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Takao MiwaDepartment of Gastroenterology, Chuno Kosei Hospital, 5-1 Wakusadori, Seki, Gifu, 501-3802, Japan. takao.miwa0505@gmail.com.ORCID http://orcid.org/0000-0002-6373-260X
Yuichiro HatanoDepartment of Tumor Pathology, Gifu University Graduate School of Medicine, Gifu, Japan.
Takahiro KochiDepartment of Gastroenterology, Chuno Kosei Hospital, 5-1 Wakusadori, Seki, Gifu, 501-3802, Japan.
Masashi AibaDepartment of Gastroenterology, Chuno Kosei Hospital, 5-1 Wakusadori, Seki, Gifu, 501-3802, Japan.
Katsuhisa TodaDepartment of Gastroenterology, Chuno Kosei Hospital, 5-1 Wakusadori, Seki, Gifu, 501-3802, Japan.
Hideko GotoDepartment of Hematology, Chuno Kosei Hospital, Gifu, Japan.
Noriaki NakamuraDepartment of Gastroenterology, Chuno Kosei Hospital, 5-1 Wakusadori, Seki, Gifu, 501-3802, Japan.
Naoki KatsumuraDepartment of Gastroenterology, Chuno Kosei Hospital, 5-1 Wakusadori, Seki, Gifu, 501-3802, Japan.
Kenji ImaiDepartment of Gastroenterology, Gifu University Graduate School of Medicine, Gifu, Japan.
Masahito ShimizuDepartment of Gastroenterology, Gifu University Graduate School of Medicine, Gifu, Japan.
Gifu University · JPMiwa Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spur cell anemia is an acquired hemolytic anemia associated with liver cirrhosis and is characterized by the presence of increased large red blood cells, which are covered with spike-like projections that vary in width, length, and distribution. A 26-year-old man was referred to our hospital presenting with jaundice, lower limb edema, and dyspnea. The patient was subsequently diagnosed with spur cell anemia related to alcoholic liver cirrhosis. Spur cell anemia is an independent predictor of mortality in liver cirrhosis and has been associated with extremely poor prognosis. The most effective treatment for spur cell anemia is liver transplantation. As seen in the literature, the treatment of spur cell anemia without liver transplantation is quite challenging. This report highlights the importance of management and treatment strategies, including control of fluid retention, blood transfusion, plasma diafiltration, and administration of diuretics. Our treatment strategies might be useful in patients who are not candidate of liver transplantation or patients waiting for liver transplantation.

Indexed as

Anemia, HemolyticLiver TransplantationAdultHumansLiver CirrhosisLiver Cirrhosis, AlcoholicMalePrognosisAlcoholic liver cirrhosisCase reportLiver cirrhosisPlasma diafiltrationSpur cell anemia

Identifiers

PMID32472376
PMCPMC7259740
OpenAlexW3031228778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.