ArticleAnnals of biomedical engineering2020
Computational Tools for the Reliability Assessment and the Engineering Design of Procedures and Devices in Bariatric Surgery.
Article in Annals of biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Ex vivo, in vivo and in silico studies of corneal biomechanics: a systematic review.Physical and engineering sciences in medicine · 2024Pooled it
- Mechanical experimentation of the gastrointestinal tract: a systematic review.Biomechanics and modeling in mechanobiology · 2024Pooled it
- Patient-Specific Constitutive Models Based on Biaxial and Microstructural Characterisation of Fresh Human Gastric Tissue.Annals of biomedical engineering · 2026Article
- How does sutures pattern influence stomach motility after endoscopic sleeve gastroplasty? A computational study.Updates in surgery · 2024Article
- Mechanical characterization of porcine ureter for the evaluation of tissue-engineering applications.Frontiers in bioengineering and biotechnology · 2024Article
- Biomechanics of Hollow Organs: Experimental Testing and Computational Modeling.Bioengineering (Basel, Switzerland) · 2023Article
- Patient-specific stomach biomechanics before and after laparoscopic sleeve gastrectomy.Surgical endoscopy · 2022Article
- Computational evaluation of laparoscopic sleeve gastrectomy.Updates in surgery · 2021Article
- Biomechanical Investigation of the Stomach Following Different Bariatric Surgery Approaches.Bioengineering (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Obesity is one of the main health concerns worldwide. Bariatric Surgery (BS) is the gold standard treatment for severe obesity. Nevertheless, unsatisfactory weight loss and complications can occur. The efficacy of BS is mainly defined on experiential bases; therefore, a more rational approach is required. The here reported activities aim to show the strength of experimental and computational biomechanics in evaluating stomach functionality depending on bariatric procedure. The experimental activities consisted in insufflation tests on samples of swine stomach to assess the pressure-volume behaviour both in pre- and post-surgical configurations. The investigation pertained to two main bariatric procedures: adjustable gastric banding (AGB) and laparoscopic sleeve gastrectomy (LSG). Subsequently, a computational model of the stomach was exploited to validate and to integrate results from experimental activities, as well as to broad the investigation to a wider scenario of surgical procedures and techniques. Furthermore, the computational approach allowed analysing stress and strain fields within stomach tissues because of food ingestion. Such fields elicit mechanical stimulation of gastric receptors, contributing to release satiety signals. Pressure-volume curves assessed stomach capacity and stiffness according to the surgical procedure. Both AGB and LSG proved to reduce stomach capacity and to increase stiffness, with markedly greater effect for LSG. At an internal pressure of 5 kPa, outcomes showed that in pre-surgical configuration the inflated volume was about 1000 mL, after AGB the inflated volume was slightly lower, while after LSG it fell significantly, reaching 100 mL. Computational modelling techniques showed the influence of bariatric intervention on mechanical stimulation of gastric receptors due to food ingestion. AGB markedly enhanced the mechanical stimulation within the fundus region, while LSG significantly reduced stress and strain intensities. Further computational investigations revealed the potentialities of hybrid endoscopic procedures to induce both reduction of stomach capacity and enhancement of gastric receptors mechanical stimulation. In conclusion, biomechanics proved to be useful for the investigation of BS effects. Future exploitations of the biomechanical methods may largely improve BS reliability, efficacy and penetration rate.
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Registered trials
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