Evidence map›Paper›PMID 32472349›Full record

ArticleIndian journal of pediatrics2021

Dynamic Distribution and Clinical Value of Peripheral Lymphocyte Subsets in Children with Infectious Mononucleosis.

Liling Chen, Xinyuan Chen, Weifeng Yao, Xin Wei, Yujie Jiang, Jingjing Guan, Xiaoyuan Liu, Yaosheng Xie, Hong Lu, Jingjing Qian and 3 more

Abstract read
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In one paragraph

Article in Indian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Liling Chen *School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Xinyuan Chen *Department of Clinical Laboratory, Wenzhou Central Hospital, Wenzhou, China.
Weifeng YaoDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, OuHai District, Wenzhou, 325000, People's Republic of China.
Xin WeiDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Yujie JiangDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, OuHai District, Wenzhou, 325000, People's Republic of China.
Jingjing GuanDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, OuHai District, Wenzhou, 325000, People's Republic of China.
Xiaoyuan LiuSchool of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Yaosheng XieDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, OuHai District, Wenzhou, 325000, People's Republic of China.
Hong LuDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, OuHai District, Wenzhou, 325000, People's Republic of China.
Jingjing QianDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, OuHai District, Wenzhou, 325000, People's Republic of China.
Zhuo ZhangDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, OuHai District, Wenzhou, 325000, People's Republic of China.
Lianfeng WuDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, OuHai District, Wenzhou, 325000, People's Republic of China.
Xiangyang LinDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, OuHai District, Wenzhou, 325000, People's Republic of China. linxy1968@126.com.ORCID 0000-0002-8926-9887
Wenzhou Medical University · CNAnhui Medical University · CNWenzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the dynamic change of peripheral lymphocyte subsets and its clinical value in children with infectious mononucleosis (IM).

methodsThirty-six pediatric patients with IM, 19 children with IM-like symptoms but lacking the serological pattern compatible with EB virus infection, and 33 healthy children were enrolled. The changes of peripheral lymphocyte subsets were detected by flow cytometry on admission and on the fifth day of antiviral treatment, respectively. Indicators of liver function and routine blood count were also detected. Besides, the receiver operating characteristic (ROC) curve and the correlation of related indicators was analyzed.

resultsWhen IM patients were admitted, the frequency and absolute number of T, CD4

conclusionsPeripheral lymphocyte subsets are closely related to the condition of children with IM, and each subset plays a relatively different role in the diagnosis and evaluation of IM.

Indexed as

Infectious MononucleosisChildFlow CytometryHumansKiller Cells, NaturalLymphocyte CountLymphocyte SubsetsT-Lymphocyte SubsetsLymphocyte subsets. Infectious mononucleosis. CD4−CD8+T cells. DPT cells

Identifiers

PMID32472349
OpenAlexW3029279682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.