Observational studyInternational journal of clinical pharmacy2020
Association of health literacy and cognition levels with severity of adverse drug reactions in cancer patients: a South Asian experience.
Observational study in International journal of clinical pharmacy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Pooled it
- Determinants, Pathways, and Outcomes of Health Literacy in India: A System Dynamics Modelling Study.Cureus · 2025Review
- Impact of health literacy on healthcare outcomes in hospitalized patients in Lebanon including quality of life and antibiotic knowledge.Scientific reports · 2025Article
- Do We Have a Knowledge Gap with Our Patients?-On the Problems of Knowledge Transfer and the Implications at the End of Life.International journal of environmental research and public health · 2025Article
- Frequency, management and impact of adverse events on treatment outcomes in patients with multidrug resistant tuberculosis in Balochistan, Pakistan.Journal of pharmaceutical policy and practice · 2024Article
- Assessment Tools for Measuring Health Literacy and Digital Health Literacy in a Hospital Setting: A Scoping Review.Healthcare (Basel, Switzerland) · 2023Article
- Research Gap in Health Literacy: Are We Overlooking a Possible Solution to Inadequate Cancer Screening in India?Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Using machine learning to develop a clinical prediction model for SSRI-associated bleeding: a feasibility study.BMC medical informatics and decision making · 2023Article
- A Comprehensive Neuropsychological Study of Familial Hypercholesterolemia and Its Relationship with Psychosocial Functioning: A Biopsychosocial Approach.Brain sciences · 2022Article
- Knowledge of patients with sarcoma about their illness-a cross-sectional questionnaire-based study (KNOWSARC).Ecancermedicalscience · 2022Article
- Artificial Intelligence-Powered Smartphone App to Facilitate Medication Adherence: Protocol for a Human Factors Design Study.JMIR research protocols · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Background The occurrence of adverse drug reactions with chemotherapy among cancer patients is a well-documented phenomenon. However, the understanding of contributoring factors and their influence on the severity of adverse drug reactions is incomplete without the psychosocial factors affecting them. Objective The present study was done to understand if factors like Health literacy and cognition levels have an association with the severity of adverse drug reactions of cancer chemotherapy. Setting This study was done in the Department of Medical Oncology in a tertiary care hospital in India. Method Two hundred and twenty-four patients meeting the study inclusion and exclusion criteria took part in the study. Details of adverse drug reactions were collected as per the central drugs standard control organization format and severity of adverse drug reactions assessed with National Cancer Institute common terminology criteria of adverse events, version 5.0. Health Literacy and Cognition Levels of patients were assessed using standardized questionnaires, i.e., Short test of functional health literacy in adults and short portable mental status questionnaire, respectively. Data were anonymized and analyzed using Statistical Package for Social Sciences version 16.0 software. Pearson's Chi square test (p value ≤ 0.05 was considered statistically significant) was used to study the associations. Main outcome measure The associations of Health Literacy and Cognition Levels with the severity of adverse drug reactions. Result We found that both Health Literacy and Cognition Levels had a statistically significant association with Grade 3 and above adverse drug reactions in cancer patients receiving chemotherapy. Conclusion An initial assessment of Health Literacy and Cognition Levels in cancer patients by cancer care providers can help identify patients at high risk of developing severe adverse drug reactions. Interventional measures for improving Health Literacy by healthcare providers can help reduce the overall burden of disease on the patient due to adverse drug reactions.
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