Evidence map›Paper›PMID 32472273›Full record

ArticleEuropean radiology2020

Influence of contrast agent and spatial resolution on myocardial strain results using feature tracking MRI.

Florian von Knobelsdorff-Brenkenhoff, Tobias Schunke, Stephanie Reiter, Roland Scheck, Berthold Höfling, Günter Pilz

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In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Comparison between conventional and compressed sensing cine cardiovascular magnetic resonance for feature tracking global circumferential strain assessment.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Florian von Knobelsdorff-BrenkenhoffDepartment of Cardiology, Clinic Agatharied, Ludwig-Maximilians-University of Munich, Norbert-Kerkel-Platz, Hausham, Agatharied, 83734, Munich, Germany. florian.vonknobelsdorff@khagatharied.de.ORCID http://orcid.org/0000-0003-0745-6062
Tobias SchunkeDepartment of Cardiology, Clinic Agatharied, Ludwig-Maximilians-University of Munich, Norbert-Kerkel-Platz, Hausham, Agatharied, 83734, Munich, Germany.
Stephanie ReiterDepartment of Cardiology, Clinic Agatharied, Ludwig-Maximilians-University of Munich, Norbert-Kerkel-Platz, Hausham, Agatharied, 83734, Munich, Germany.
Roland ScheckRadiology Oberland, Clinic Agatharied, Ludwig-Maximilians-University of Munich, Agatharied, Munich, Germany.
Berthold HöflingDepartment of Cardiology, Clinic Agatharied, Ludwig-Maximilians-University of Munich, Norbert-Kerkel-Platz, Hausham, Agatharied, 83734, Munich, Germany.
Günter PilzDepartment of Cardiology, Clinic Agatharied, Ludwig-Maximilians-University of Munich, Norbert-Kerkel-Platz, Hausham, Agatharied, 83734, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesFeature tracking for assessing myocardial strain from cardiac magnetic resonance (CMR) cine images detects myocardial deformation abnormalities with prognostic implication, e.g., in myocardial infarction and cardiomyopathy. Standards for image acquisition and processing are not yet available. Study aim was analyzing the influence of spatial resolution and contrast agent on myocardial strain results.

methodsSeventy-five patients underwent CMR for analyzing peak systolic circumferential, longitudinal, and radial strain. Group A included n = 50 with normal left ventricular ejection fraction, no wall motion abnormality, and no fibrosis on late enhancement imaging. Group B included n = 25 with chronic myocardial infarct. For feature tracking, steady-state free precession cine images were acquired repeatedly. (1) Native standard cine (spatial resolution 1.4 × 1.4 × 8 mm

resultsLower spatial resolution was associated with elevated longitudinal strain (- 21.7% vs. - 19.8%; p < 0.001) in viable myocardium in group A, and with elevated longitudinal (- 17.0% vs. - 14.3%; p = 0.001), circumferential (- 18.6% vs. - 14.6%; p = 0.002), and radial strain (36.8% vs. 31.0%; p = 0.013) in infarcted myocardium in group B. Gadolinium administration was associated with reduced circumferential (- 21.4% vs. - 22.3%; p = 0.001) and radial strain (44.4% vs. 46.9%; p = 0.016) in group A, whereas strain results of the infarcted tissue in group B did not change after contrast agent administration.

conclusionsVariations in spatial resolution and the administration of contrast agent may influence myocardial strain results in viable and partly in infarcted myocardium. Standardized image acquisition seems important for CMR feature tracking. KEY POINTS: • Feature tracking is used for calculating myocardial strain from cardiac magnetic resonance (CMR) cine images. • This prospective study demonstrated that CMR strain results may be influenced by spatial resolution and by the administration of gadolinium-based contrast agent. • The results underline the need for standardized image acquisition for CMR strain analysis, with constant imaging parameters and without contrast agent.

Indexed as

AgedCardiomyopathiesContrast MediaFemaleFibrosisHumansMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardiumProspective StudiesVentricular Function, LeftContrast MediaGadoterate meglumineMagnetic resonance imagingMyocardial contractionMyocardial strainSystole

Identifiers

PMID32472273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.