Evidence map›Paper›PMID 32472266›Full record

GuidelineEuropean journal of pediatrics2020

EAU-ESPU guidelines recommendations for daytime lower urinary tract conditions in children.

Serdar Tekgul, Raimund Stein, Guy Bogaert, Shabnam Undre, Rien J M Nijman, Josine Quaedackers, Lisette 't Hoen, Radim Kocvara, Mesrur Selcuk Silay, Christian Radmayr and 1 more

Registry-linked trialOpen access · bronzeAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in European journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07242898 (Clinically Important or Just Statistically Significant? Minimal Clinically Important Difference for DVISS and PIN-Q in Children With Urinary Incontinence), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07242898 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Clinically Important or Just Statistically Significant? Minimal Clinically Important Difference for DVISS and PIN-Q in Children With Urinary Incontinence

TypeinterventionalSponsorArtvin Coruh UniversityRan2026 to 2026Enrolled100ConditionsUrinary IncontinenceArmsStandard Urotherapy (SU)
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Observational
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  7. Article
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  14. Updates of Overactive Bladder in Pediatrics.International neurourology journal · 2023
    Article
  15. Article
  16. Pediatric Nephrolithiasis.Healthcare (Basel, Switzerland) · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. First North American experience of propiverine use in children with overactive bladder.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 7 countries.

Serdar TekgulDivision of Pediatric Urology, Department of Urology, School of Medicine, Hacettepe University, Ankara, Turkey. serdartekgul@gmail.com.
Raimund SteinDepartment of Pediatric, Adolescent and Reconstructive Urology, University of Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Guy BogaertDepartment of Urology, University of Leuven, Leuven, Belgium.
Shabnam UndreDepartment of Pediatric and Adult Urology, East and North Hertfordshire NHS Trust, Stevenage, UK.
Rien J M NijmanDepartment of urology and pediatric urology, University Medical Centre Groningen, Groningen, The Netherlands.
Josine QuaedackersDepartment of urology and pediatric urology, University Medical Centre Groningen, Groningen, The Netherlands.
Lisette 't HoenDepartment of Urology, Erasmus MC, Rotterdam, The Netherlands.
Radim KocvaraDepartment of Urology, General Teaching Hospital and Charles University 1st Faculty of Medicine in Praha, Prague, Czech Republic.
Mesrur Selcuk SilayDivision of Pediatric Urology, Department of Urology, Istanbul Gelisim University and Istanbul Memorial Hospital, Istanbul, Turkey.
Christian RadmayrDepartment of Urology, Medical University of Innsbruck, Innsbruck, Austria.
Hasan Serkan DoganDivision of Pediatric Urology, Department of Urology, School of Medicine, Hacettepe University, Ankara, Turkey.
Hacettepe University · TRUniversity Medical Center Groningen · NLCharles University · CZEast and North Hertfordshire NHS Trust · GBErasmus University Rotterdam · NLIstanbul Memorial Hospital · TRKU Leuven · BEUniversität Innsbruck · ATUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective is to review the literature related to lower urinary tract (LUT) conditions in children to conceptualize general practice guidelines for the general practitioner, pediatrician, pediatric urologist, and urologist. PubMed was searched for the last 15-year literature by the committee. All articles in peer-review journal-related LUT conditions (343) have been retrieved and 76 have been reviewed extensively. Prospective trials were few and the level of evidence was low. Most of the recommendations have been done by committee consensus after extensive discussion of literature reports. History taking is an integral part of evaluation assessing day- and nighttime urine and bowel control, urgency, and frequency symptoms. Exclusion of any neurogenic and organic cause is essential. Uroflowmetry and residual urine determination are recommended in all patients to evaluate bladder emptying. Urodynamic studies are reserved for refractory or complicated cases. Urotherapy that aims to educate the child and family about bladder and bowel function and guides them to achieve normal voiding and bowel habits should initially be employed in all cases except those who have urinary tract infections (UTI) and constipation. Specific medical treatment is added in the case of refractory overactive bladder symptoms and recurrent UTIs.Conclusion: Producing recommendations for managing LUTS in children based on high-quality studies is not possible. LUTS in children should be evaluated in a multimodal way by minimal invasive diagnostic procedures. Urotherapy is the mainstay of treatment and specific medical treatment is added in refractory cases.What is Known:• Symptoms of the lower urinary tract may have significant social consequences and sometimes clinical morbidities like urinary tract infections and vesicoureteral reflux. In many children, however, there is no such obvious cause for the incontinence, and they are referred to as having functional bladder problems.What is New:• This review aims to construct a practical recommendation strategy for the general practitioner, pediatrician, pediatric urologist, and urologist for LUTS in children. Producing recommendations for managing LUTS in children based on high-quality studies is not possible. LUTS in children should be evaluated in a multimodal way by minimal invasive diagnostic procedures. Urotherapy is the mainstay of treatment and specific medical treatment is added in refractory cases.

Indexed as

ChildCombined Modality TherapyHumansLower Urinary Tract SymptomsUrinary IncontinenceUrinary Tract InfectionsVesico-Ureteral RefluxDysfunctionIncontinenceLower urinary tractManagementPediatricTreatment

Identifiers

PMID32472266
OpenAlexW3030227177

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.