ArticleClinical oral investigations2021
Mapping the microbiological diversity of odontogenic abscess: are we using the right drugs?
Article in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Antibiotic resistance in odontogenic infections: A systematic review of current evidence and implications for guideline-based therapy.Clinical oral investigations · 2026Pooled it
- Bacterial Profile and Antibiotic Resistance in Oral and Maxillofacial Infections.Journal of clinical medicine · 2026Article
- Cultured microbial community complexity is associated with antimicrobial resistance and Enterobacterales enrichment in adult odontogenic infections.Oral and maxillofacial surgery · 2026Article
- Clinical impact of antibiotic resistance in odontogenic infections: a 12-year analysis of 740 cases.Clinical oral investigations · 2025Article
- Global trends in the microbial profile of odontogenic infections and its practical implications: A 70-year narrative review.Oral and maxillofacial surgery · 2025Review
- Swabs versus native specimens in severe head and neck infections: a prospective pilot study and suggestions for clinical management.Oral and maxillofacial surgery · 2025Article
- Deep Neck Infections: The Effectiveness of Therapeutic Management and Bacteriological Profile.Medicina (Kaunas, Lithuania) · 2025Observational
- Results of bacterial cultivation are infrequently utilized in the treatment of patients hospitalized with severe odontogenic infections - a retrospective cohort study.Journal of oral microbiology · 2025Article
- Patients with severe odontogenic infections receive insufficient dental treatment before hospitalization - a retrospective cross-sectional study.Acta odontologica Scandinavica · 2024Article
- Microbial spectrum and resistance of odontogenic abscesses - microbiological analysis using next generation sequencing.Clinical oral investigations · 2024Article
- Antibiotic susceptibility of orofacial infections in Bratislava: a 10-year retrospective study.Clinical oral investigations · 2024Article
- Rising incidence of severe maxillofacial space infections in Germany.Clinical oral investigations · 2024Article
- Microbial isolates and antibiotic sensitivity in patients hospitalized with odontogenic infections at a tertiary center over 10 years.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2023Article
- Article
- Sonication versus the conventional method for evaluation of the dental microbiome: a prospective pilot study.BMC oral health · 2022Article
- Bacteriological analysis based on disease severity and clinical characteristics in patients with deep neck space abscess.BMC infectious diseases · 2022Article
- Odontogenic Cervicofacial Necrotizing Fasciitis: Microbiological Characterization and Management of Four Clinical Cases.Pathogens (Basel, Switzerland) · 2022Article
- The Efficacy of Pyogenic Cavity Aerobic Therapy with Negative Pressure Drainage in the Treatment of Deep Neck Space Infections.Infection and drug resistance · 2021Article
- Aetiopathogenesis and Treatment Evaluation of Odontogenic Cellulitis in the Maxillofacial Region: a Retrospective Study.Journal of oral & maxillofacial researchReview
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was categorizing the microbial flora and susceptibility to antibiotics and to clarify to which degree the empiric administered antibiotics are suitable for therapy. MATERIALS AND
methodsA 3.5-year retrospective study evaluated hospital records of 206 patients who suffered from head and neck infections of odontogenic origin. All patients underwent surgical incision and drainage and received intravenous antibiotics and inpatient treatment. The specimens were obtained by performing a swab.
resultsTwo hundred six patients were included with 251 strains isolated (1.22 per patient). One hundred eight strains showed antibiotic resistance. Eighty-seven patients showed at least one bacterial strain that showed antibiotic resistance (42.2%). The most frequent isolated bacteria were Streptococcus spp. (n = 116), with a high rate of antibiotic resistance (50.8%). We investigated 205 cases of antibiotic resistance in 87 subjects. Nine bacterial strains showed no susceptibility to unacid (4.3%) and 36 strains to clindamycin (17.5%).
conclusionAntibiotic resistance against clindamycin was rather high. The distribution of the afflicted spaces and isolated bacteria was alike recent findings. It is mandatory to understand that immediate surgical treatment in terms of incision and drainage is the basis in abscess treatment. Antibiotic treatment is adjunct therapy. CLINICAL RELEVANCE: Streptococcus species were the most frequently identified bacteria presenting antibiotic resistance in more than 50%. Increased resistant rates for clindamycin require reconsiderations regarding an empiric antibiotic treatment.
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