Evidence map›Paper›PMID 32472215›Full record

ArticleEnvironmental monitoring and assessment2020

Brown bullhead at the St. Lawrence River (Cornwall) Area of Concern: health and endocrine status in the context of tissue concentrations of PCBs and mercury.

M D O Pinheiro, D B D Simmons, M Villella, G R Tetreault, D C G Muir, M E McMaster, L M Hewitt, J L Parrott, B J Park, S B Brown and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental monitoring and assessment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

M D O PinheiroDepartment of Biology, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada.
D B D SimmonsFaculty of Science, Ontario Technical University, Oshawa, Ontario, L1G 0C5, Canada.
M VillellaAquatic Contaminants Research Division, Environment and Climate Change Canada, National Water Research Institute, Burlington, ON, L7S 1A1, Canada.
G R TetreaultAquatic Contaminants Research Division, Environment and Climate Change Canada, National Water Research Institute, Burlington, ON, L7S 1A1, Canada.
D C G MuirAquatic Contaminants Research Division, Environment and Climate Change Canada, National Water Research Institute, Burlington, ON, L7S 1A1, Canada.
M E McMasterAquatic Contaminants Research Division, Environment and Climate Change Canada, National Water Research Institute, Burlington, ON, L7S 1A1, Canada.
L M HewittAquatic Contaminants Research Division, Environment and Climate Change Canada, National Water Research Institute, Burlington, ON, L7S 1A1, Canada.
J L ParrottAquatic Contaminants Research Division, Environment and Climate Change Canada, National Water Research Institute, Burlington, ON, L7S 1A1, Canada.
B J ParkToxicology Centre, University of Saskatchewan, Saskatoon, Saskatchewan, S7N 5B3, Canada.
S B BrownAquatic Contaminants Research Division, Environment and Climate Change Canada, National Water Research Institute, Burlington, ON, L7S 1A1, Canada.
J P SherryAquatic Contaminants Research Division, Environment and Climate Change Canada, National Water Research Institute, Burlington, ON, L7S 1A1, Canada. jim.sherry@canada.ca.ORCID http://orcid.org/0000-0001-6090-4480
Environment and Climate Change Canada · CAOntario Tech University · CAUniversity of Saskatchewan · CAUniversity of Waterloo · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The St. Lawrence River, at Cornwall Ontario, has accumulated sediment contaminants, mainly mercury (Hg) and polychlorinated biphenyls (PCBs), from industrial point sources over many years. Although those sources are past, the river at Cornwall remains an Area of Concern (AOC). Because of remediation and other changes in the AOC, improved knowledge of contaminants in wild-fish and their putative links to health effects could help decision makers to better assess the AOC's state. Thus, we compared tissue concentrations of Hg, PCBs, morphometric measures of health, and biomarkers of exposure, metabolic-, and reproductive health in native brown bullhead (Ameiurus nebulosus) from the AOC to those of upstream reference fish. Linear discriminant analysis separated the adult fish of both sexes among upstream and downstream sites without misclassification. Burdens of total-Hg (all sites) and PCB toxic equivalents (downstream sites) exceeded the guidance for the protection of wildlife consumers. There were subtle effects of site on physiological variables, particularly in female fish. Total-Hg in tissue correlated negatively to plasma testosterone and 17β-estradiol in female fish at Cornwall: moreover, concentrations of both hormones were lower within the AOC compared to reference site fish. A similar effect on vitellogenin, which was uncorrelated to E2/T at the downstream sites, indicated the potential for reproductive effects. Downstream fish also had altered thyroidal status (T

Indexed as

IctaluridaeMercuryPolychlorinated BiphenylsWater Pollutants, ChemicalAnimalsEnvironmental MonitoringFemaleMaleOntarioMercuryPolychlorinated BiphenylsWater Pollutants, ChemicalContaminantsFish healthHistologyLegacy contaminantsSex hormonesThyroid hormones

Identifiers

PMID32472215
OpenAlexW3030855098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.