ArticleNature communications2020
Weaker neural suppression in autism.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Prediction in Autism Spectrum Disorder: A Systematic Review of Empirical Evidence.Autism research : official journal of the International Society for Autism Research · 2021Pooled it
- Enhanced visual contrast suppression during peak psilocybin effects: Psychophysical results from a pilot randomized controlled trial.Journal of vision · 2024Trial
- Low-dose lysergic acid diethylamide alters subjective visual perception but not visual contrast surround suppression.Neuroscience of consciousness · 2026Article
- Right inferior frontal contributions to visual spatial suppression and visuomotor performance.Psychoradiology · 2026Article
- Connectivity, Computation, and Plasticity of the Early Visual System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Reduced neural suppression at occipital cortex in subthreshold depression.Translational psychiatry · 2025Article
- hMT+ activity predicts the effect of spatial attention on surround suppression.Journal of vision · 2025Article
- Linking cortical surface area to computational properties in human visual perception.iScience · 2024Article
- Polyphenols: Natural Food-Grade Biomolecules for the Treatment of Nervous System Diseases from a Multi-Target Perspective.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Visual surround suppression at the neural and perceptual levels.Cognitive neurodynamics · 2024Review
- Article
- Temporal dynamics of normalization reweighting.Journal of vision · 2023Article
- The psychosis human connectome project: Design and rationale for studies of visual neurophysiology.NeuroImage · 2023Article
- Perceptual Center-Surround Contrast Suppression in Adolescence.Investigative ophthalmology & visual science · 2023Article
- Weakened untuned gain control is associated with schizophrenia while atypical orientation-tuned suppression depends on visual acuity.Journal of vision · 2023Article
- Gamma oscillations point to the role of primary visual cortex in atypical motion processing in autism.PloS one · 2023Article
- Haploinsufficiency of Shank3 increases the orientation selectivity of V1 neurons.Scientific reports · 2022Article
- Visual illusion susceptibility in autism: A neural model.The European journal of neuroscience · 2022Article
- Investigating the neurochemistry of the human visual system using magnetic resonance spectroscopy.Brain structure & function · 2022Review
- Awareness-Dependent Normalization Framework of Visual Bottom-up Attention.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Abnormal sensory processing has been observed in autism, including superior visual motion discrimination, but the neural basis for these sensory changes remains unknown. Leveraging well-characterized suppressive neural circuits in the visual system, we used behavioral and fMRI tasks to demonstrate a significant reduction in neural suppression in young adults with autism spectrum disorder (ASD) compared to neurotypical controls. MR spectroscopy measurements revealed no group differences in neurotransmitter signals. We show how a computational model that incorporates divisive normalization, as well as narrower top-down gain (that could result, for example, from a narrower window of attention), can explain our observations and divergent previous findings. Thus, weaker neural suppression is reflected in visual task performance and fMRI measures in ASD, and may be attributable to differences in top-down processing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.