ArticleNature communications2020
Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
What it found
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The trial behind it
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Who cites it
74 citing papers in PubMed.
- Four-Dimensional Electrochemiluminescence Microscopy Enables Depth-Resolved Imaging of Single, Living Spheroids.Angewandte Chemie (International ed. in English) · 2026Article
- Synergistic sensitization between Rh-MOF and Ru(bpy)Mikrochimica acta · 2026Article
- Mechanistic insights into electrochemiluminescence: fueling advances in bioanalysis and imaging.Chemical science · 2026Review
- Electrochemiluminescence and Photoinduced Electrochemiluminescence Probing of Energy Conversion Catalysis.Chemical & biomedical imaging · 2026Review
- Article
- Localized Accumulation of Tri-n-Propylamine Prolongs Electrochemiluminescence for Tumor Model Spheroid Analysis.Angewandte Chemie (International ed. in English) · 2026Article
- Versatile Electrochemiluminescence Imaging Platform for Multiplexed Biosensing and Point-of-Care Application.Chemical & biomedical imaging · 2026Article
- Advances, Challenges, and Opportunities in Electrochemiluminescence Bioimaging.Chemical & biomedical imaging · 2026Review
- Recent Advances in Electrochemiluminescence Imaging Applications.Chemical & biomedical imaging · 2026Review
- Integrating Electrochemistry and Optical Imaging to Probe Phospholipid Architectures: Emerging Paradigms in Fluorescence and Electrochemiluminescence Studies.Chemical & biomedical imaging · 2026Review
- Fluorescence spectroelectrochemistry for the study of electrochemiluminescence of the CdTe quantum dots/tripropylamine coreactant system.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026Article
- Synthesis of Two Oligocarbazoles Enabling Efficient Dopamine Detection.Precision chemistry · 2026Article
- Rationalized Volcano Plot in Heterogeneous Electrochemiluminescence.ACS electrochemistry · 2026Article
- Recent Proceedings of Advanced Electrochemiluminescence Imaging Technology and Applications in Accurate Analysis.Chemical & biomedical imaging · 2026Review
- From Microscale to Nanoscale Shadow Electrochemiluminescence Microscopy.Angewandte Chemie (International ed. in English) · 2026Article
- An Enhanced Electrochemiluminescence Immunoassay Platform via Optimized Magnetic Bead Uniformity for Reliable Thyroid-Stimulating Hormone Monitoring.Bioengineering (Basel, Switzerland) · 2026Article
- Radical Electroprecipitation Prolongs "Electro"chemiluminescence of the Tris(2,2'-bipyridyl)ruthenium(II) and Tri-Journal of the American Chemical Society · 2026Article
- Bright Circularly Polarized Electrochemiluminescence from Heterobinuclear IrAngewandte Chemie (International ed. in English) · 2026Article
- Boosting Electrochemiluminescence of Carbon Nitrides via Molecular Capacitor-Mediated Spatiotemporal Electron Coordination.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Electrochemiluminescence Modulation by a Versatile Organic Redox Mediator.Angewandte Chemie (International ed. in English) · 2025Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrochemiluminescence (ECL) is a powerful transduction technique with a leading role in the biosensing field due to its high sensitivity and low background signal. Although the intrinsic analytical strength of ECL depends critically on the overall efficiency of the mechanisms of its generation, studies aimed at enhancing the ECL signal have mostly focused on the investigation of materials, either luminophores or coreactants, while fundamental mechanistic studies are relatively scarce. Here, we discover an unexpected but highly efficient mechanistic path for ECL generation close to the electrode surface (signal enhancement, 128%) using an innovative combination of ECL imaging techniques and electrochemical mapping of radical generation. Our findings, which are also supported by quantum chemical calculations and spin trapping methods, led to the identification of a family of alternative branched amine coreactants, which raises the analytical strength of ECL well beyond that of present state-of-the-art immunoassays, thus creating potential ECL applications in ultrasensitive bioanalysis.
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