Evidence map›Paper›PMID 32471987›Full record

ArticleNature communications2020

The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABA

Xin Zhou, Marine Gueydan, Maelle Jospin, Tingting Ji, Aurore Valfort, Bérangère Pinan-Lucarré, Jean-Louis Bessereau

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. ImmatureProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Frontiers in aging neuroscience · 2026
    Review
  5. Article
  6. ImmaturebioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Post-synaptic GABACell reports · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. The regulatory landscape of neurite development inFrontiers in molecular neuroscience · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 3 countries.

Xin ZhouUniv Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, Institut NeuroMyoGène, 69008, Lyon, France.ORCID http://orcid.org/0000-0002-8667-0309
Marine GueydanUniv Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, Institut NeuroMyoGène, 69008, Lyon, France.
Maelle JospinUniv Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, Institut NeuroMyoGène, 69008, Lyon, France.
Tingting JiUniv Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, Institut NeuroMyoGène, 69008, Lyon, France.
Aurore ValfortUniv Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, Institut NeuroMyoGène, 69008, Lyon, France.
Bérangère Pinan-Lucarré *Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, Institut NeuroMyoGène, 69008, Lyon, France. berangere.pinan-lucarre@univ-lyon1.fr.
Jean-Louis Bessereau *Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, Institut NeuroMyoGène, 69008, Lyon, France. jean-louis.bessereau@univ-lyon1.fr.ORCID http://orcid.org/0000-0002-3088-7621
Université Claude Bernard Lyon 1 · FR

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Increasing evidence indicates that guidance molecules used during development for cellular and axonal navigation also play roles in synapse maturation and homeostasis. In C. elegans the netrin receptor UNC-40/DCC controls the growth of dendritic-like muscle cell extensions towards motoneurons and is required to recruit type A GABA receptors (GABA

Indexed as

AnimalsAxon GuidanceCaenorhabditis elegansCaenorhabditis elegans ProteinsCell Adhesion MoleculesCell Adhesion Molecules, NeuronalCytoskeletal ProteinsHelminth ProteinsMembrane ProteinsNerve Tissue ProteinsNeuromuscular JunctionReceptors, Cell SurfaceReceptors, GABA-ASynapsesSynaptic TransmissionCaenorhabditis elegans ProteinsCell Adhesion MoleculesCell Adhesion Molecules, NeuronalCytoskeletal ProteinsHelminth ProteinsLin-2 protein, C elegansMADD-4 protein, C elegansMembrane ProteinsNerve Tissue Proteinsneuroligin 1Receptors, Cell SurfaceReceptors, GABA-AUNC-40 protein, C elegans

Identifiers

PMID32471987
PMCPMC7260190
OpenAlexW3028970347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.