ArticleProceedings of the National Academy of Sciences of the United States of America2020
Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Experimental temperatures shape host microbiome diversity and composition.Global change biology · 2023Pooled it
- Novel Distance Regression for Repeated Outcomes With Missing Data: Applications to Longitudinal and Crossover Studies of Microbiome Beta-Diversity.Statistics in medicine · 2026Article
- Article
- Broad-spectrum antibiotic treatment reshapes the gut microbiome, resistome, and colonization potential of opportunistic pathogens: a metagenomics study.Gut pathogens · 2026Article
- Recipients' native bacteria determine the outcome of FMT treatment in inflammatory bowel disease.Gut microbes · 2025Article
- Functional archetypes in the human gut microbiome reveal metabolic diversity, stability, and influence disease-associated signatures.Microbiome · 2025Article
- Molecular mechanisms of gut microbiota dysbiosis and metabolites in Alzheimer's disease pathogenesis: implications for precision therapeutics.Molecular brain · 2025Review
- Medical digital twins: enabling precision medicine and medical artificial intelligence.The Lancet. Digital health · 2025Review
- Warming-driven migration of enterotypes mediates host health and disease statuses in ectotherm Litopenaeus vannamei.Communications biology · 2025Article
- Mechanisms underlying alterations of the gut microbiota by exercise and their role in shaping ecological resilience.FEMS microbiology reviews · 2025Review
- Wise Roles and Future Visionary Endeavors of Current Emperor: Advancing Dynamic Methods for Longitudinal Microbiome Meta-Omics Data in Personalized and Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Spatiotemporal dynamics during niche remodeling by super-colonizing microbiota in the mammalian gut.Cell systems · 2024Article
- Transient colonizing microbes promote gut dysbiosis and functional impairment.NPJ biofilms and microbiomes · 2024Article
- Revealing Interactions of Gut Microbiota and Metabolite in Confined Environments Using High-Throughput Sequencing and Metabolomic Analysis.Nutrients · 2024Article
- Prediction of anastomotic insufficiency based on the mucosal microbiome prior to colorectal surgery: a proof-of-principle study.Scientific reports · 2024Article
- Dimension reduction of microbiome data linked Bifidobacterium and Prevotella to allergic rhinitis.Scientific reports · 2024Article
- Microbial Ecology and Metabolism of Emerging Adulthood: Gut Microbiome Insights from a College Freshman Cohort.Gut microbes reports · 2024Article
- Gut microbiome diversity, variability, and latent community types compared with shifts in body weight during the freshman year of college in dormitory-housed adolescents.Gut microbes · 2023Observational
- A streamlined pipeline based on HmmUFOtu for microbial community profiling using 16S rRNA amplicon sequencing.Genomics & informatics · 2023Article
- Global branches and local states of the human gut microbiome define associations with environmental and intrinsic factors.Nature communications · 2023Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Pioneer 100 Wellness Project involved quantitatively profiling 108 participants' molecular physiology over time, including genomes, gut microbiomes, blood metabolomes, blood proteomes, clinical chemistries, and data from wearable devices. Here, we present a longitudinal analysis focused specifically around the Pioneer 100 gut microbiomes. We distinguished a subpopulation of individuals with reduced gut diversity, elevated relative abundance of the genus
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.