ArticleProceedings of the National Academy of Sciences of the United States of America2020
Redox controls metabolic robustness in the gas-fermenting acetogen
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 85 citations in OpenAlex.
- Thermodynamic metabolic modeling of growth and bioproduction potential of the acetogenSynthetic and systems biotechnology · 2026Article
- The potential of syngas as a central mediator for a carbon-agnostic circular economy.Nature communications · 2026Review
- Systems-level analysis predicts no autotrophy-linked protein-RNA interactions in Clostridium autoethanogenum.Nature communications · 2026Article
- Carbon-monoxide-driven bioethanol production operates through a tungsten-dependent catalyst.Nature chemical biology · 2026Article
- A megatransposon drives the adaptation of Thermoanaerobacter kivui to carbon monoxide.Nature communications · 2025Article
- Understanding microbial syngas fermentation rates.Applied microbiology and biotechnology · 2024Review
- Acetate Shock Loads Enhance CO Uptake Rates of Anaerobic Microbiomes.Microbial biotechnology · 2024Article
- Clostridium autoethanogenum alters cofactor synthesis, redox metabolism, and lysine-acetylation in response to elevated HBiotechnology for biofuels and bioproducts · 2024Article
- Harnessing acetogenic bacteria for one-carbon valorization toward sustainable chemical production.RSC chemical biology · 2024Review
- Adaptive laboratory evolution of Clostridium autoethanogenum to metabolize COMicrobial biotechnology · 2024Article
- The role of ethanol oxidation during carboxydotrophic growth of Clostridium autoethanogenum.Microbial biotechnology · 2023Article
- Synergistic investigation of natural and synthetic C1-trophic microorganisms to foster a circular carbon economy.Nature communications · 2023Review
- Downscaling Industrial-Scale Syngas Fermentation to Simulate Frequent and Irregular Dissolved Gas Concentration Shocks.Bioengineering (Basel, Switzerland) · 2023Article
- Overflow metabolism at the thermodynamic limit of life: How carboxydotrophic acetogens mitigate carbon monoxide toxicity.Microbial biotechnology · 2023Article
- Leveraging substrate flexibility and product selectivity of acetogens in two-stage systems for chemical production.Microbial biotechnology · 2023Review
- High methanol-to-formate ratios induce butanol production in Eubacterium limosum.Microbial biotechnology · 2022Article
- Article
- Metabolic Engineering Interventions for Sustainable 2,3-Butanediol Production in Gas-FermentingmSystems · 2022Article
- EstablishingApplied and environmental microbiology · 2022Article
- Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale.Nature biotechnology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Living biological systems display a fascinating ability to self-organize their metabolism. This ability ultimately determines the metabolic robustness that is fundamental to controlling cellular behavior. However, fluctuations in metabolism can affect cellular homeostasis through transient oscillations. For example, yeast cultures exhibit rhythmic oscillatory behavior in high cell-density continuous cultures. Oscillatory behavior provides a unique opportunity for quantitating the robustness of metabolism, as cells respond to changes by inherently compromising metabolic efficiency. Here, we quantify the limits of metabolic robustness in self-oscillating autotrophic continuous cultures of the gas-fermenting acetogen
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Registered trials
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