Evidence map›Paper›PMID 32471907›Full record

ArticleHeart (British Cardiac Society)2020

Computed tomographic myocardial mass compared with invasive myocardial perfusion measurement.

Daniëlle C J Keulards, Stephane Fournier, Marcel van 't Veer, Iginio Colaiori, Jo M Zelis, Mohamed El Farissi, Frederik M Zimmermann, Carlos Collet, Bernard De Bruyne, Nico H J Pijls

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Heart (British Cardiac Society), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Article
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  5. Coronary flow and resistance patterns indexed by subtended myocardial mass in coronary microvascular dysfunction.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
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  8. Review
  9. Article
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  11. Absolute coronary blood flow across different endotypes of ANOCA.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Article
  12. Absolute coronary flow and microvascular resistance before and after transcatheter aortic valve implantation.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Article
  13. Changes in absolute coronary flow and microvascular resistance during exercise in patients with ANOCA.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Article
  14. Article
  15. Observational
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  19. Invasive evaluation of coronary microvascular dysfunction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Review
  20. Coronary Physiology: Delivering Precision Medicine?Reviews in cardiovascular medicine · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Daniëlle C J Keulards *Department of Cardiology, Catharina Hospital, Eindhoven, North Brabant, The Netherlands danielle.keulards@catharinaziekenhuis.nl.ORCID 0000-0002-0913-4967
Stephane Fournier *Department of Cardiology, University Hospital of Lausanne, Lausanne, Switzerland.
Marcel van 't VeerDepartment of Cardiology, Catharina Hospital, Eindhoven, North Brabant, The Netherlands.
Iginio ColaioriDepartment of Cardiology, Cardiovascular Center Aalst, OLV Clinic Aalst, Leopoldlaan, Belgium.
Jo M ZelisDepartment of Cardiology, Catharina Hospital, Eindhoven, North Brabant, The Netherlands.ORCID 0000-0003-2110-4901
Mohamed El FarissiDepartment of Cardiology, Catharina Hospital, Eindhoven, North Brabant, The Netherlands.
Frederik M ZimmermannDepartment of Cardiology, Catharina Hospital, Eindhoven, North Brabant, The Netherlands.
Carlos ColletDepartment of Cardiology, Cardiovascular Center Aalst, OLV Clinic Aalst, Leopoldlaan, Belgium.
Bernard De BruyneDepartment of Cardiology, University Hospital of Lausanne, Lausanne, Switzerland.
Nico H J PijlsDepartment of Cardiology, Catharina Hospital, Eindhoven, North Brabant, The Netherlands.
Radboud University Nijmegen · NLOnze Lieve Vrouwziekenhuis Hospital · BEUniversity Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe prognostic importance of a coronary stenosis depends on its functional severity and its depending myocardial mass. Functional severity can be assessed by fractional flow reserve (FFR), estimated non-invasively by a specific validated CT algorithm (FFR

methodsIn this exploratory study, 35 patients with (near) normal coronary arteries underwent CT scanning for computed flow-based CTmass assessment and underwent invasive myocardial perfusion measurement in all 3 major coronary arteries by continuous thermodilution. Next, the mass and flows were calculated as relative percentages of total mass and perfusion.

resultsThe mean difference between CTmass per territory and invasively measured myocardial perfusion, both expressed as percentage of total mass and perfusion, was 5.3±6.2% for the left anterior descending territory, -2.0±7.4% for the left circumflex territory and -3.2±3.4% for the right coronary artery territory. The intraclass correlation between the two techniques was 0.90.

conclusionsOur study shows a close relationship between the relative mass of the perfusion territory calculated by the specific CT algorithm and invasively measured myocardial perfusion. As such, these data support the use of CTmass to estimate territorial myocardium-at-risk in proximal coronary arteries.

Indexed as

Computed Tomography AngiographyCoronary AngiographyFractional Flow Reserve, MyocardialMultidetector Computed TomographyMyocardial Perfusion ImagingAgedAlgorithmsCoronary StenosisCoronary VesselsFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRadiographic Image Interpretation, Computer-AssistedCardiac catheterisation and angiographycardiac computed tomographic (CT) imaging

Identifiers

PMID32471907
PMCPMC7509389
OpenAlexW3030142560

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.