ArticleJournal of the American Society of Nephrology : JASN2020
Prevalence and Risk Factors for CKD in the General Population of Southwestern Nicaragua.
Article in Journal of the American Society of Nephrology : JASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Environmental risk factors for chronic kidney disease of non-traditional causes in tropical coastal areas: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2025Pooled it
- Global health inequalities of chronic kidney disease: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Pooled it
- The Association of Arsenic Metabolism and Blood Pressure: A Cross-Sectional Analysis in the MesoAmerican Nephropathy Occupational Study (MANOS).Research square · 2026Article
- Mesoamerican nephropathy: A silent epidemic at the nexus of climate, labor, and health.AIMS public health · 2026Article
- Association between alcohol consumption and chronic kidney disease: a population-based survey.Clinical and experimental nephrology · 2024Article
- Population-level detection of early loss of kidney function: 7-year follow-up of a young adult cohort at risk of Mesoamerican nephropathy.International journal of epidemiology · 2024Article
- Prevalence and associated risk factors for chronic kidney disease in the elderly physically disabled population in Shanghai, China: a cross-sectional study.BMC public health · 2023Article
- A nomogram for predicting the 4-year risk of chronic kidney disease among Chinese elderly adults.International urology and nephrology · 2023Review
- Observational
- Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala.Revista panamericana de salud publica = Pan American journal of public health · 2023Article
- Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study.Frontiers in nutrition · 2023Article
- Solving the riddle of Aguascalientes nephropathy: nephron number, environmental toxins and family clustering.Clinical kidney journal · 2022Article
- Article
- Where do you live and what do you do? Two questions that might impact your kidney health.Frontiers in nephrology · 2022Review
- Prevalence and associated risk factors of chronic kidney disease: A case study within SIME clinics in Quito, Ecuador 2019-2021.Frontiers in medicine · 2022Article
- Aguascalientes: one of the hottest chronic kidney disease (CKD) hotspots in Mexico and a CKD of unknown aetiology mystery to be solved.Clinical kidney journal · 2021Article
- Prevalence and Risk Factors for Chronic Kidney Disease in Belize: A Population-based Survey.Lancet regional health. Americas · 2021Article
- Population Estimates of GFR and Risk Factors for CKD in Guatemala.Kidney international reports · 2021Article
- CKD and CKDu in northern Peru: a cross-sectional analysis under the DEGREE protocol.BMC nephrology · 2021Article
- Community-based screening to determine the prevalence, health and nutritional status of patients with CKD in rural and peri-urban Bangladesh.Therapeutic advances in chronic disease · 2021Article
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies have described Mesoamerican nephropathy among agricultural workers of El Salvador and northwestern Nicaragua. Data on prevalence and risk factors for CKD beyond agricultural workers and in other regions in Nicaragua are sparse.
methodsWe recruited participants from 32 randomly selected communities in the Department of Rivas's ten municipalities in two phases. In phase 1, we screened participants using a field-based capillary creatinine measuring system and collected self-reported information on lifestyle and occupational, exposure, and health histories. Two years later, in phase 2, we enrolled 222 new participants, performing serum creatinine testing in these participants and confirmatory serum creatinine testing in phase 1 participants.
resultsWe enrolled 1242 of 1397 adults (89%) living in 533 households (median age 41 years; 43% male). We confirmed CKD (eGFR<60 ml/min per 1.73 m
conclusionsAdjusted CKD prevalence was about 5% with repeat confirmatory testing in southwest Nicaragua, lower than in the northwest region. Risk factors included diabetes, hypertension, and current or prior work in the sugarcane industry but not in other forms of agricultural work. Formal CKD surveillance programs in Nicaragua are needed to assess the overall burden of CKD nationally, with a focus on agricultural workers.
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