Evidence map›Paper›PMID 32471481›Full record

ArticleVeterinary research2020

Experimental Coxiella burnetii infection in non-pregnant goats and the effect of breeding.

Hendrik I J Roest, Annemieke Dinkla, Ad P Koets, Jacob Post, Lucien van Keulen

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Molecular characterization ofFrontiers in veterinary science · 2026
    Article
  4. Article
  5. Applied and environmental microbiology · 2024
    Article
  6. Longitudinal surveillance ofFrontiers in veterinary science · 2024
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hendrik I J RoestDepartment of Bacteriology and Epidemiology, Wageningen Bioveterinary Research, Lelystad, The Netherlands. h.i.j.roest@minlnv.nl.ORCID http://orcid.org/0000-0003-1987-7470
Annemieke DinklaDepartment of Bacteriology and Epidemiology, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
Ad P KoetsDepartment of Bacteriology and Epidemiology, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
Jacob PostDepartment of Virology, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
Lucien van KeulenDepartment of Infection Biology, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
Wageningen University & Research · NLMinistry of Agriculture, Nature and Food Quality · NLUtrecht University · NL

Funding

Ministry of Agriculture, Nature and Food Qualtiy KB-12-005.01-003
6 · The paper itself

Abstract

Q fever is a zoonosis caused by the intracellular bacterium Coxiella burnetii. In Europe, small ruminants are the main source of human Q fever. Small ruminant herds can be infectious during several lambing seasons. However, it is not clear how infection is maintained in a herd and what role non-pregnant animals play in the transmission of C. burnetii. We therefore inoculated nulliparous goats with C. burnetii, isolated from the outbreak of Q fever in the Netherlands, to gain a better understanding of the role of non-pregnant goats. Seroconversion and excretion of C. burnetii were monitored after inoculation. To study the effect of breeding on the excretion of C. burnetii, the goats were naturally bred and monitored during gestation and after lambing. Our results indicate that C. burnetii infection prior to breeding did not result in infection of the placenta nor did it affect the gestation length or the number of kids born. However, one of the ten does did excrete C. burnetii in the colostrum post-partum and the bacterium was detected in the mammary gland and associated lymph nodes at necropsy. This result indicates that non-pregnant goats might play a role in maintaining Q fever in a goat herd as persistent carriers of infection.

Indexed as

Air MicrobiologyAnimalsBreedingColostrumCoxiella burnetiiFecesFemaleGoat DiseasesGoatsMilkQ FeverVagina

Identifiers

PMID32471481
PMCPMC7257221
OpenAlexW3030664216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.