Evidence map›Paper›PMID 32471439›Full record

ArticleBiomedical engineering online2020

Automated computer-assisted detection system for cerebral aneurysms in time-of-flight magnetic resonance angiography using fully convolutional network.

Geng Chen, Xia Wei, Huang Lei, Yang Liqin, Li Yuxin, Dai Yakang, Geng Daoying

Open access · goldAbstract read
In one paragraph

Article in Biomedical engineering online, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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  9. [Automatic detection method of intracranial aneurysms on maximum intensity projection images based on SE-CaraNet].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Geng ChenAcademy for Engineering and Technology, Fudan University, 20 Handan Road, Shanghai, 200433, China.ORCID http://orcid.org/0000-0003-4008-6833
Xia WeiAcademy for Engineering and Technology, Fudan University, 20 Handan Road, Shanghai, 200433, China.
Huang LeiDepartment of Radiology, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai, 200040, China.
Yang LiqinDepartment of Radiology, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai, 200040, China.
Li YuxinDepartment of Radiology, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai, 200040, China.
Dai YakangSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, 88 Keling Road, Suzhou, 215163, China. daiyk@sibet.ac.cn.
Geng DaoyingDepartment of Radiology, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai, 200040, China. gengdy@163.com.
Fudan University · CNChinese Academy of Sciences · CN

Funding

Jiangsu Provincial Key Research and Development Program BE2017663Lishui Key Technology Research Development Program 2019ZDYF09Lishui Key Technology Research Development Program 2019ZDYF17National Key Research and Development Plan 2018YFC0116904National Natural Science Foundation of China 61672236Suzhou Industry Technological Innovation Projects SYG201707Suzhou Science and Technology Development Project SZS201818
6 · The paper itself

Abstract

backgroundAs the rupture of cerebral aneurysm may lead to fatal results, early detection of unruptured aneurysms may save lives. At present, the contrast-unenhanced time-of-flight magnetic resonance angiography is one of the most commonly used methods for screening aneurysms. The computer-assisted detection system for cerebral aneurysms can help clinicians improve the accuracy of aneurysm diagnosis. As fully convolutional network could classify the image pixel-wise, its three-dimensional implementation is highly suitable for the classification of the vascular structure. However, because the volume of blood vessels in the image is relatively small, 3D convolutional neural network does not work well for blood vessels.

resultsThe presented study developed a computer-assisted detection system for cerebral aneurysms in the contrast-unenhanced time-of-flight magnetic resonance angiography image. The system first extracts the volume of interest with a fully automatic vessel segmentation algorithm, then uses 3D-UNet-based fully convolutional network to detect the aneurysm areas. A total of 131 magnetic resonance angiography image data are used in this study, among which 76 are training sets, 20 are internal test sets and 35 are external test sets. The presented system obtained 94.4% sensitivity in the fivefold cross-validation of the internal test sets and obtained 82.9% sensitivity with 0.86 false positive/case in the detection of the external test sets.

conclusionsThe proposed computer-assisted detection system can automatically detect the suspected aneurysm areas in contrast-unenhanced time-of-flight magnetic resonance angiography images. It can be used for aneurysm screening in the daily physical examination.

Indexed as

Magnetic Resonance AngiographyNeural Networks, ComputerAdolescentAdultAgedAutomationDiagnosis, Computer-AssistedFemaleHumansImage Processing, Computer-AssistedIntracranial AneurysmMaleMiddle AgedTime FactorsYoung AdultCerebral aneurysmComputer-assisted detectionFully convolutional networkTOF-MRA

Identifiers

PMID32471439
PMCPMC7257213
OpenAlexW3028977306

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.