Evidence map›Paper›PMID 32471416›Full record

ArticleBMC nephrology2020

Association of simple renal cysts and chronic kidney disease with large abdominal aortic aneurysm.

Milena Miszczuk, Verena Müller, Christian E Althoff, Andrea Stroux, Daniela Widhalm, Andy Dobberstein, Andreas Greiner, Helena Kuivaniemi, Irene Hinterseher

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Milena MiszczukVascular Surgery Clinic, Klinik für Gefäßchirurgie, Campus Charité Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany.
Verena MüllerSurgical Clinic, Campus Charité Mitte and Campus Virchow-Klinikum, Berlin, Germany.
Christian E AlthoffInstitute of Radiology, Campus Charité Mitte, Berlin, Germany.
Andrea StrouxInstitute of Medical Biometrics and Clinical Epidemiology, Campus Charité Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Daniela WidhalmVascular Surgery Clinic, Klinik für Gefäßchirurgie, Campus Charité Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany.
Andy DobbersteinVascular Surgery Clinic, Klinik für Gefäßchirurgie, Campus Charité Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany.
Andreas GreinerVascular Surgery Clinic, Klinik für Gefäßchirurgie, Campus Charité Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany.
Helena KuivaniemiDivision of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
Irene HinterseherVascular Surgery Clinic, Klinik für Gefäßchirurgie, Campus Charité Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany. irene.hinterseher@charite.de.ORCID 0000-0001-6725-525X
Franklin University · USCharité - Universitätsmedizin Berlin · DEStellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbdominal aortic aneurysms (AAA) primarily affect men over 65 years old who often have many other diseases, with similar risk factors and pathobiological mechanisms to AAA. The aim of this study was to assess the prevalence of simple renal cysts (SRC), chronic kidney disease (CKD), and other kidney diseases (e.g. nephrolithiasis) among patients presenting with AAA.

methodsTwo groups of patients (97 AAA and 100 controls), with and without AAA, from the Surgical Clinic Charité, Berlin, Germany, were selected for the study. The control group consisted of patients who were evaluated for a kidney donation (n = 14) and patients who were evaluated for an early detection of a melanoma recurrence (n = 86). The AAA and control groups were matched for age and sex. Medical records were analyzed and computed tomography scans were reviewed for the presence of SRC and nephrolithiasis.

resultsSRC (74% vs. 57%; p<0.016) and CKD (30% vs. 8%; p<0.001) were both more common among AAA than control group patients. On multivariate analysis, CKD, but not SRC, showed a strong association with AAA.

conclusionsKnowledge about pathobiological mechanisms and association between CKD and AAA could provide better diagnostic and therapeutic approaches for these patients.

Indexed as

AgedAged, 80 and overAortic Aneurysm, AbdominalCase-Control StudiesComputed Tomography AngiographyCystsFemaleGermanyHumansMaleMiddle AgedNephrolithiasisPrevalenceRenal Insufficiency, ChronicRetrospective StudiesAbdominal aortic aneurysmchronic kidney diseaserenal cyst

Identifiers

PMID32471416
PMCPMC7257207
OpenAlexW3030105852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.