ArticleBMC pediatrics2020
Late-onset neonatal sepsis in Suzhou, China.
Article in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- [Expert consensus on the diagnosis and treatment of common neonatal diseases in primary healthcare institutions: neonatal sepsis (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Construction and evaluation of a neonatal septic shock prediction model based on multimodal data.Medicine · 2025Article
- Time to recovery of neonatal sepsis and its predictors in public hospitals of North Shoa Zone, Central Ethiopia.BMC infectious diseases · 2025Article
- Advancing Understanding ofMicroorganisms · 2025Article
- Disease burden comparison and associated risk factors of early- and late-onset neonatal sepsis in China and the USA, 1990-2019.Global health action · 2024Article
- Antimicrobial susceptibility profiles of invasive bacterial infections among children from low- and middle-income countries in the Western Pacific Region (WPRO) - a systematic review and meta-analysis.The Lancet regional health. Western Pacific · 2024Article
- Bacteriological Profile and Antibiotic Susceptibility of Neonatal Sepsis Cases in the Neonatal Intensive Care Unit of a Tertiary Hospital in Türkiye.Children (Basel, Switzerland) · 2024Article
- Trends in Causative Organisms and Antimicrobial Resistance in Late-onset Neonatal Sepsis.Turkish archives of pediatrics · 2024Article
- Impacts of COVID-19 pandemic on culture-proven sepsis in neonates.Frontiers in cellular and infection microbiology · 2024Article
- Quality improvement in neonatal care through enhanced patient safety and clinical risk management: a before-and-after study about neonatal sepsis.Frontiers in medicine · 2024Article
- Risk Factors Associated with Multi-Drug Resistance in Neonatal Sepsis Caused byInfection and drug resistance · 2023Article
- Developmental Population Pharmacokinetics-Pharmacodynamics of Meropenem in Chinese Neonates and Young Infants: Dosing Recommendations for Late-Onset Sepsis.Children (Basel, Switzerland) · 2022Article
- Progress in Diagnosis and Treatment of Neonatal Sepsis: A Review Article.JNMA; journal of the Nepal Medical Association · 2022Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to describe the causative organisms of neonatal late-onset sepsis (LOS) and their antimicrobial resistance in Suzhou, Southeast China over a 7-year period.
methodsWe performed a retrospective study on neonates with LOS from Jan1, 2011 to Dec 31, 2017. The demographic, clinical, and laboratory data of neonates with LOS were analyzed. Logistic regression was used to investigate the risk factors with mortality.
resultsDuring the study period, 202 neonates with LOS were finally identified. The most common pathogens were Escherichia coli (29.2%), followed by Klebsiella pneumoniae (19.3%), and Coagulase-negative Staphylococcus (CoNS) (16.8%). Nearly 90% of the K. pneumoniae were resistant to cefazolin and 71.8% to ceftazidime. Thirty-four patients (16.8%) died. Multivariable logistic regression showed that significant predictors of mortality were birth weight < 1500 g, respiratory distress and convulsions.
conclusionsGram-negative organisms have an important role in LOS in our region, with high levels of resistance to third-generation cephalosporins. These data may help in the selection of antibiotics for empirical treatment of neonates with sepsis.
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