Evidence map›Paper›PMID 32471257›Full record

ArticleCancers2020

The Role of Vitamin D Receptor Gene Polymorphisms in Colorectal Cancer Risk.

Ippokratis Messaritakis, Asimina Koulouridi, Maria Sfakianaki, Konstantinos Vogiatzoglou, Nikolaos Gouvas, Elias Athanasakis, John Tsiaoussis, Evangelos Xynos, Dimitriοs Mavroudis, Maria Tzardi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Vitamin D receptor gene polymorphisms and its interactions with environmental factors on renal cell carcinoma risk.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021
    Article
  15. Heterogeneity of Colorectal Cancer Progression: Molecular Gas and Brakes.International journal of molecular sciences · 2021
    Review
  16. Vitamin D Receptor (Nutrients · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ippokratis MessaritakisLaboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.ORCID 0000-0003-1877-500X
Asimina KoulouridiLaboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.
Maria SfakianakiLaboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.
Konstantinos VogiatzoglouLaboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.
Nikolaos GouvasMedical School, University of Cyprus, 20537 Nicosia, Cyprus.
Elias AthanasakisDepartment of General Surgery, Heraklion University Hospital, 71110 Heraklion, Greece.
John TsiaoussisDepartment of Anatomy, School of Medicine, University of Crete, 70013 Heraklion, Greece.
Evangelos XynosDepartment of Surgery, Creta Interclinic Hospital of Heraklion, 71305 Heraklion, Greece.
Dimitriοs MavroudisLaboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.
Maria TzardiLaboratory of Pathology, University General Hospital of Heraklion, 70013 Heraklion, Greece.
John SouglakosLaboratory of Translational Oncology, Medical School, University of Crete, 70013 Heraklion, Greece.
University of Crete · GRUniversity Hospital of Heraklion · GRUniversity of Cyprus · CY

Funding

Gastrointestinal Cancer Study Group n/aHellenic Society of Medical Oncology n/a
6 · The paper itself

Abstract

Vitamin D deficiency has been associated with increased colorectal cancer (CRC) incidence risk and mortality. Vitamin D mediates its action through the binding of the vitamin D receptor (VDR), and polymorphisms of the VDR might explain these inverse associations. The aim of the study was the investigation of the relevance of rs731236;

Indexed as

colorectal cancerpolymorphismstoll-like receptorsvitamin D receptors

Identifiers

PMID32471257
PMCPMC7352496
OpenAlexW3032275883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.