Evidence map›Paper›PMID 32471245›Full record

ArticleInternational journal of molecular sciences2020

Identification of Selective Novel Hits against

Dorothy Wavinya Nyamai, Özlem Tastan Bishop

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Kaempferol activity onPharmaceutical biology · 2026
    Article
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  5. Review
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  10. The Structural Basis ofMolecules (Basel, Switzerland) · 2022
    Article
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  13. Article
  14. MDM-TASK-web: MD-TASK and MODE-TASK web server for analyzing protein dynamics.Computational and structural biotechnology journal · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dorothy Wavinya NyamaiResearch Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.
Özlem Tastan BishopResearch Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.
Rhodes University · ZA

Funding

the National Research Foundation (NRF) South Africa 105267
6 · The paper itself

Abstract

Recently, there has been increased interest in aminoacyl tRNA synthetases (aaRSs) as potential malarial drug targets. These enzymes play a key role in protein translation by the addition of amino acids to their cognate tRNA. The aaRSs are present in all

Indexed as

Allosteric SiteAdenosine TriphosphateAmino Acyl-tRNA SynthetasesBiological ProductsCatalytic DomainEnzyme InhibitorsHumansMolecular Docking SimulationPlasmodium falciparumProtein BindingProtozoan ProteinsAdenosine TriphosphateAmino Acyl-tRNA SynthetasesBiological ProductsEnzyme Inhibitorsprolyl T RNA synthetaseProtozoan Proteinsallosteric modulatorsAminoacyl tRNA synthetasedynamic residue networkfree energy landscapeMD-TASKvirtual screening

Identifiers

PMID32471245
PMCPMC7312540
OpenAlexW3030437205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.