Evidence map›Paper›PMID 32471244›Full record

ArticlePharmaceutics2020

Validation of Pharmacological Protocols for Targeted Inhibition of Canalicular MRP2 Activity in Hepatocytes Using [

Solène Marie, Irene Hernández-Lozano, Louise Breuil, Wadad Saba, Anthony Novell, Jean-Luc Gennisson, Oliver Langer, Charles Truillet, Nicolas Tournier

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Hepatobiliary PET with [EJNMMI research · 2025
    Article
  2. Article
  3. Review
  4. Pharmacokinetic Imaging UsingPharmaceuticals (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Solène MarieUniversité Paris-Saclay, CEA, Inserm, CNRS, BioMaps, Service Hospitalier Frédéric Joliot, 4 place du Général Leclerc, 91401 Orsay, France.ORCID 0000-0001-5247-4871
Irene Hernández-LozanoDepartment of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-3700-7690
Louise BreuilUniversité Paris-Saclay, CEA, Inserm, CNRS, BioMaps, Service Hospitalier Frédéric Joliot, 4 place du Général Leclerc, 91401 Orsay, France.
Wadad SabaUniversité Paris-Saclay, CEA, Inserm, CNRS, BioMaps, Service Hospitalier Frédéric Joliot, 4 place du Général Leclerc, 91401 Orsay, France.
Anthony NovellUniversité Paris-Saclay, CEA, Inserm, CNRS, BioMaps, Service Hospitalier Frédéric Joliot, 4 place du Général Leclerc, 91401 Orsay, France.
Jean-Luc GennissonUniversité Paris-Saclay, CEA, Inserm, CNRS, BioMaps, Service Hospitalier Frédéric Joliot, 4 place du Général Leclerc, 91401 Orsay, France.
Oliver LangerDepartment of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
Charles TruilletUniversité Paris-Saclay, CEA, Inserm, CNRS, BioMaps, Service Hospitalier Frédéric Joliot, 4 place du Général Leclerc, 91401 Orsay, France.
Nicolas TournierUniversité Paris-Saclay, CEA, Inserm, CNRS, BioMaps, Service Hospitalier Frédéric Joliot, 4 place du Général Leclerc, 91401 Orsay, France.ORCID 0000-0002-0755-2030
Centre National de la Recherche Scientifique · FRAustrian Institute of Technology · ATMedical University of Vienna · AT

Funding

Agence Nationale de la Recherche ANR-11-INBS-0006.
6 · The paper itself

Abstract

The multidrug resistance-associated protein 2 (MRP2) mediates the biliary excretion of drugs and metabolites. [

Indexed as

drug-induced liver injurydrug metabolismimaginglivermembrane transporterpharmacokinetics

Identifiers

PMID32471244
PMCPMC7355955
OpenAlexW3031325065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.