ArticleNutrients2020
Inflammation Adjustment by Two Methods Decreases the Estimated Prevalence of Zinc Deficiency in Malawi.
Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Malaria infection confounds inflammation-adjusted micronutrient biomarker concentrations in children and women in Malawi: a secondary analysis of the 2015/2016 Malawi micronutrient survey.The British journal of nutrition · 2025Article
- The 4T and 7T introgressions fromFrontiers in plant science · 2024Article
- Agronomic biofortification increases grain zinc concentration of maize grown under contrasting soil types in Malawi.Plant direct · 2022Article
- Soil and landscape factors influence geospatial variation in maize grain zinc concentration in Malawi.Scientific reports · 2022Article
- Article
- Zinc deficiency as a possible risk factor for increased susceptibility and severe progression of Corona Virus Disease 19.The British journal of nutrition · 2022Review
- The potential of spot urine as a biomarker for zinc assessment in Malawian children and adults.Frontiers in nutrition · 2022Article
- Re-Defining the Population-Specific Cut-Off Mark for Vitamin A Deficiency in Pre-School Children of Malawi.Nutrients · 2021Article
- Article
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
Serum zinc concentration (SZC) is used widely to assess population-level zinc status. Its concentration decreases during inflammatory responses, which can affect the interpretation of the results. This study aimed to re-estimate the prevalence of zinc deficiency in Malawi based on the 2015-2016 Malawi Micronutrient Survey (MNS) data, by adjusting SZC measures with markers of inflammation. SZC and inflammation data from 2760 participants were analysed. Adjustments were made using: (1) The Internal Correction Factor (ICF) method which used geometric means, and (2) The Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) method, which used linear regression. Mean SZC values increased significantly when adjustments were made by either ICF or BRINDA (
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Registered trials
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