Evidence map›Paper›PMID 32471077›Full record

ArticleSensors (Basel, Switzerland)2020

Automated Detection of Presymptomatic Conditions in Spinocerebellar Ataxia Type 2 Using Monte Carlo Dropout and Deep Neural Network Techniques with Electrooculogram Signals.

Catalin Stoean, Ruxandra Stoean, Miguel Atencia, Moloud Abdar, Luis Velázquez-Pérez, Abbas Khosravi, Saeid Nahavandi, U Rajendra Acharya, Gonzalo Joya

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. An Improved Hybrid Approach for Handling Class Imbalance Problem.Arabian journal for science and engineering · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 6 countries.

Catalin StoeanRomanian Institute of Science and Technology, 400022 Cluj-Napoca, Romania.
Ruxandra StoeanRomanian Institute of Science and Technology, 400022 Cluj-Napoca, Romania.
Miguel AtenciaDepartment of Applied Mathematics, Universidad de Málaga, 29071 Málaga, Spain.ORCID 0000-0002-5158-5905
Moloud AbdarInstitute for Intelligent Systems Research and Innovation (IISRI), Deakin University, 3216 Victoria, Australia.
Luis Velázquez-PérezCuban Academy of Sciences, La Habana 10100, Cuba.
Abbas KhosraviInstitute for Intelligent Systems Research and Innovation (IISRI), Deakin University, 3216 Victoria, Australia.
Saeid NahavandiInstitute for Intelligent Systems Research and Innovation (IISRI), Deakin University, 3216 Victoria, Australia.
U Rajendra AcharyaDepartment of Electronics and Computer Engineering, Ngee Ann Polytechnic, 599489 Clementi, Singapore.ORCID 0000-0003-2689-8552
Gonzalo JoyaDepartment of Electronic Technology, Universidad de Málaga, 29071 Málaga, Spain.
Deakin University · AURomanian Institute of Science and Technology · ROUniversidad de Málaga · ESAsia University · TW

Funding

Ministerio de Ciencia e Innovación TIN2017-88728-C2-1-RUniversidad de Málaga Project DIATAX
6 · The paper itself

Abstract

Application of deep learning (DL) to the field of healthcare is aiding clinicians to make an accurate diagnosis. DL provides reliable results for image processing and sensor interpretation problems most of the time. However, model uncertainty should also be thoroughly quantified. This paper therefore addresses the employment of Monte Carlo dropout within the DL structure to automatically discriminate presymptomatic signs of spinocerebellar ataxia type 2 in saccadic samples obtained from electrooculograms. The current work goes beyond the common incorporation of this special type of dropout into deep neural networks and uses the uncertainty derived from the validation samples to construct a decision tree at the register level of the patients. The decision tree built from the uncertainty estimates obtained a classification accuracy of 81.18% in automatically discriminating control, presymptomatic and sick classes. This paper proposes a novel method to address both uncertainty quantification and explainability to develop reliable healthcare support systems.

Indexed as

ElectrooculographyMonte Carlo MethodNeural Networks, ComputerSpinocerebellar AtaxiasDecision TreesHumansImage Processing, Computer-Assisteddecision treesdeep learningelectrooculogrammedicineMonte Carlo dropoutsensor datauncertainty quantification

Identifiers

PMID32471077
PMCPMC7309035
OpenAlexW3032297297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.