Evidence map›Paper›PMID 32471032›Full record

ArticleInternational journal of molecular sciences2020

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer.

Hagma H Workel, Nienke van Rooij, Annechien Plat, Diana C J Spierings, Rudolf S N Fehrmann, Hans W Nijman, Marco de Bruyn

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. CD39-Expressing CD8Cancers · 2023
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. CD39 Regulation and Functions in T Cells.International journal of molecular sciences · 2021
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hagma H WorkelDepartment of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Nienke van RooijDepartment of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Annechien PlatDepartment of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Diana C J SpieringsEuropean Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0001-8403-474X
Rudolf S N FehrmannDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Hans W NijmanDepartment of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Marco de BruynDepartment of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.

Funding

Dutch Cancer Society/Alpe d'Huzes RUG 2013-5960Dutch Cancer Society/Alpe d'Huzes UMCG 2014-6719The Netherlands Organization for Scientific Research (NWO-VENI grant) 916-16025
6 · The paper itself

Abstract

Tumor-infiltrating CD8+ T cells (TIL) are of the utmost importance in anti-tumor immunity. CD103 defines tumor-resident memory T cells (T

Indexed as

Antigens, CDCD8-Positive T-LymphocytesCytotoxicity, ImmunologicDactinomycinEndometrial NeoplasmsFemaleGene Expression Regulation, NeoplasticGenotypeGranulocyte-Macrophage Colony-Stimulating FactorHumansImmune Checkpoint InhibitorsInterleukin-21InterleukinsIonomycinLymphocyte ActivationLymphocytes, Tumor-InfiltratingAntigens, CDDactinomycinGranulocyte-Macrophage Colony-Stimulating FactorImmune Checkpoint InhibitorsInterleukin-21InterleukinsIonomycinRNA, MessengerTetradecanoylphorbol AcetateCD103CD39cytokinesisendometrial cancerIL-21tissue-resident memory celltranscript stability

Identifiers

PMID32471032
PMCPMC7312498

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.