Evidence map›Paper›PMID 32470891›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2020

Cervical human papillomavirus DNA detection in women living with HIV and HIV-uninfected women living in Limbe, Cameroon.

Adebola Adedimeji, Rogers Ajeh, Anastase Dzudie, Ernestine Kendowo, Norbert Fuhngwa, Denis Nsame, Andre Gaetan Simo-Wambo, Enow Orock, Tiffany M Hebert, Amanda J Pierz and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Adebola AdedimejiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Rogers AjehClinical Research Education, Networking and Consultancy, Yaoundé, Cameroon.
Anastase DzudieClinical Research Education, Networking and Consultancy, Yaoundé, Cameroon.
Ernestine KendowoClinical Research Education, Networking and Consultancy, Yaoundé, Cameroon.
Norbert FuhngwaClinical Research Education, Networking and Consultancy, Yaoundé, Cameroon.
Denis NsameLimbe Regional Hospital, Limbe, Southwest Region, Cameroon.
Andre Gaetan Simo-WamboLimbe Regional Hospital, Limbe, Southwest Region, Cameroon.
Enow OrockDepartment of Biomedical Sciences, University of Buea, Cameroon.
Tiffany M HebertDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Amanda J PierzDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Daniel MurokoraBrick By Brick, Kampala, Uganda.
Kathryn AnastosDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Philip E CastleDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address: philip.castle@einsteinmed.org.
Albert Einstein College of Medicine · USLimbe Provincial Hospital · CMUniversity of Buea · CM

Funding

WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI STEVEN C. ALMO · 1985 to 2026
$111.2M
"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
NCI NIH HHS P30 CA013330NIAID NIH HHS U01 AI096299
6 · The paper itself

Abstract

backgroundThere are limited data on cervical HPV prevalence in Cameroon and none from its Anglophone region. We investigated cervical HPV prevalence in HIV-uninfected (HIV[-]) and HIV-infected (WLWH) women living in the region.

methodsA convenience sample of consecutively recruited HIV[-] women (n = 295) and women living with HIV (WLWH) (n = 560) attending the Limbé Regional Hospital were enrolled into a cervical screening study. Women underwent screening that included HPV testing of self-collected and provider-collected specimens. We calculated the HPV prevalence by HIV status, overall and stratified by age, and among WLWH, stratified by CD4 counts. We compared the concordance for the detection of HPV between self- and provider-collected specimens.

resultsCrude HPV prevalence was 21.69 % (95 % confidence interval [95 %CI] = 17.21-26.48 %) for HIV[-] women and 46.43 % (95 %CI = 42.24-50.66 %) for WLWH (p < 0.001). Among WLWH, older age (p

conclusionsHIV-related immunosuppression was a risk factor for HPV prevalence in this population. HPV testing of self-collected specimens appeared to be less specific than HPV testing of provider-collected specimens.

Indexed as

AdultAge FactorsCameroonCD4 Lymphocyte CountCervix UteriDNA, ViralEarly Detection of CancerFemaleGenotypeHIV InfectionsHumansImmunocompromised HostMass ScreeningMiddle AgedPapillomaviridaePapillomavirus InfectionsDNA, ViralCervical cancerHuman immunodeficiency virus (HIV)Human papillomavirus (HPV)ScreeningSelf-collection

Identifiers

PMID32470891
PMCPMC7809577
OpenAlexW3028105502

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.