Evidence map›Paper›PMID 32470298›Full record

ArticleJournal of medicinal chemistry2020

Jelena Konstantinović, Samir Yahiaoui, Alaa Alhayek, Jörg Haupenthal, Esther Schönauer, Anastasia Andreas, Andreas M Kany, Rolf Müller, Jesko Koehnke, Fabian K Berger and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Multiparameter Optimization ofJournal of medicinal chemistry · 2026
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  6. Review
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  8. Review
  9. Article
  10. Inhibition of Collagenase Q1 ofAdvanced therapeutics · 2022
    Article
  11. Using Structure-guided Fragment-Based Drug Discovery to TargetFrontiers in molecular biosciences · 2022
    Review
  12. Article
  13. Article
  14. RSC medicinal chemistry · 2021
    Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Jelena KonstantinovićDepartment of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.
Samir YahiaouiDepartment of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.ORCID 0000-0001-5134-5007
Alaa AlhayekDepartment of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.
Jörg HaupenthalDepartment of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.
Esther SchönauerDepartment of Biosciences, University of Salzburg, Billrothstr. 11, 5020 Salzburg, Austria.ORCID 0000-0002-2625-9446
Anastasia AndreasDepartment of Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.
Andreas M KanyDepartment of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.
Rolf MüllerDepartment of Pharmacy, Saarland University, Campus Building E8.1, 66123 Saarbrücken, Germany.
Jesko KoehnkeWorkgroup Structural Biology of Biosynthetic Enzymes, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus Building E8.1, 66123 Saarbrücken, Germany.
Fabian K BergerInstitute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg/Saar, Germany.
Markus BischoffInstitute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg/Saar, Germany.
Rolf W HartmannDepartment of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.ORCID 0000-0002-5871-5231
Hans BrandstetterDepartment of Biosciences, University of Salzburg, Billrothstr. 11, 5020 Salzburg, Austria.ORCID 0000-0002-6089-3045
Anna K H HirschDepartment of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.ORCID 0000-0001-8734-4663
Helmholtz Centre for Infection Research · DEInstitute of Medical Microbiology and Hygiene · DEUniversity of Salzburg · ATHelmholtz Institute for Pharmaceutical Research Saarland · DE

Funding

Austrian Science Fund FWF P 31843
6 · The paper itself

Abstract

In light of the global antimicrobial-resistance crisis, there is an urgent need for novel bacterial targets and antibiotics with novel modes of action. It has been shown that

Indexed as

AnimalsAnti-Bacterial AgentsBacterial ProteinsCell LineClostridium InfectionsCollagenasesHathewaya histolyticaHumansMatrix Metalloproteinase InhibitorsMetalloendopeptidasesPseudomonas aeruginosaPseudomonas InfectionsSuccinimidesSwineZebrafishAnti-Bacterial AgentsBacterial ProteinsCollagenasesMatrix Metalloproteinase InhibitorsMetalloendopeptidasespseudolysin, Pseudomonas aeruginosaSuccinimides

Identifiers

PMID32470298
PMCPMC7429951
OpenAlexW3032515986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.