ArticlePloS one2020
Environmental DNA: A promising factor for tuberculosis risk assessment in multi-host settings.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Non-invasive environmental DNA sampling reveals tuberculosis risks at the human - Great Ape Interface in Africa.Emerging microbes & infections · 2026Article
- An unprecedented outbreak of Salmonella enterica serovar Enteritidis in kept Iberian wild goats (Capra pyrenaica).BMC veterinary research · 2026Article
- Tracking pathogen-related markers with eDNA in natural areas: how environmental factors shape surveillance strategies.Veterinary research · 2026Article
- Metabolomic signatures of tuberculosis and paratuberculosis in goats revealed by high-resolution and benchtop NMR spectroscopy.Veterinary research · 2025Article
- Wildlife risk mitigation protocols reduce risk species visits and pathogen marker detection in open-air farms.Veterinary research · 2025Article
- Sponge-based environmental DNA detection as a useful tool in monitoring Mycobacterium tuberculosis complex markers in European bison (Bison bonasus).Scientific reports · 2025Article
- Evidence ofFrontiers in veterinary science · 2025Article
- Establishment and application of a TaqMan-based quantitative PCR assay for simultaneous detection of bovineFrontiers in microbiology · 2025Article
- One Health Farming: Noninvasive monitoring reveals links between farm vertebrate richness and pathogen markers in outdoor hoofstock.One health (Amsterdam, Netherlands) · 2024Article
- Population structure and history ofMicrobiology spectrum · 2024Article
- A one health-focused literature review on bovine and zoonotic tuberculosis in Pakistan from the past two decades: challenges and way forward for control.One health (Amsterdam, Netherlands) · 2024Review
- Non-invasive surveillance of shared pathogens in the Eurasian brown bear (One health (Amsterdam, Netherlands) · 2024Article
- Evaluation of the Effect of a Recent Comparative Intradermal Tuberculin Test on the Humoral Diagnosis of Paratuberculosis Using Serum and Milk Samples from Goats.Veterinary sciences · 2024Article
- Host-, Environment-, or Human-Related Effects Drive Interspecies Interactions in an Animal Tuberculosis Multi-Host Community Depending on the Host and Season.Transboundary and emerging diseases · 2024Article
- Bovine tuberculosis in Spain, is it really the final countdown?Irish veterinary journal · 2023Review
- Article
- Evaluation of the clinical evolution and transmission of SARS-CoV-2 infection in cats by simulating natural routes of infection.Veterinary research communications · 2022Article
- HEPA filters of portable air cleaners as a tool for the surveillance of SARS-CoV-2.Indoor air · 2022Article
- Large-scale study on virological and serological prevalence of SARS-CoV-2 in cats and dogs in Spain.Transboundary and emerging diseases · 2022Article
- Environment and Offspring Surveillance in Porcine Brucellosis.Frontiers in veterinary science · 2022Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Attaining and maintaining the Official Tuberculosis Free status continues to be a challenge when several domestic and wild hosts contribute to the maintenance of the Mycobacterium tuberculosis complex (MTC). Local tuberculosis hotspots are sometimes identified in cattle in low-prevalence regions. We have, therefore, studied one such hotspot in depth in order to produce an epidemiological diagnosis. Host population size and MTC prevalence were estimated in selected wildlife and in livestock, while on-cattle environmental DNA detection was additionally used as a proxy for risk of exposure at the farm (herd) level. Positive skin test reactors were found on16 of the 24 cattle farms studied in the period 2012-2016. Although all goats tested negative to the skin test during this period, MTC was confirmed in four sheep at slaughter, thus indicating an unknown prevalence of infection in this host species. With regard to wildlife, the prevalence of MTC infection based on culture was 8.8% in the case of wild boar (Sus scrofa), and the only road-killed badger (Meles meles) submitted for culture tested positive. Two criteria were employed to divide the cattle farms into higher or lower risk: tuberculosis testing results and environmental DNA detection. Environmental MTC DNA detection yielded significant differences regarding "use of regional pastures" and "proximity to woodland". This study suggests that on-animal environmental DNA sampling may help when assessing contact risk as regards MTC in livestock at the herd level. This tool opens up new avenues of epidemiological research in complex multi-host settings.
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