Evidence map›Paper›PMID 32469997›Full record

ArticlePloS one2020

The yield of community-based tuberculosis and HIV among key populations in hotspot settings of Ethiopia: A cross-sectional implementation study.

Z G Dememew, D Jerene, D G Datiko, N Hiruy, A Tadesse, T Moile, D Bekele, G Yismawu, K Melkieneh, B Reshu and 1 more

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In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Z G DememewManagement Sciences for Health (MSH), Challenge TB Project, Addis Ababa, Ethiopia.ORCID 0000-0002-4428-6050
D JereneManagement Sciences for Health (MSH), Challenge TB Project, Addis Ababa, Ethiopia.
D G DatikoManagement Sciences for Health (MSH), Challenge TB Project, Addis Ababa, Ethiopia.
N HiruyManagement Sciences for Health (MSH), Challenge TB Project, Addis Ababa, Ethiopia.
A TadesseHarari Health Bureau, Harar, Ethiopia.
T MoileDire Dawa Health Bureau, Dire Dawa, Ethiopia.
D BekeleOromia Regional Health Bureau, Addis Ababa, Ethiopia.
G YismawuAmhara Regional Health Bureau, Bahirdar, Ethiopia.
K MelkienehManagement Sciences for Health (MSH), Challenge TB Project, Addis Ababa, Ethiopia.
B ReshuManagement Sciences for Health (MSH), Challenge TB Project, Addis Ababa, Ethiopia.
P G SuarezManagement Sciences for Health, Arlington, Virginia, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the yield of tuberculosis (TB) and the prevalence of Human Immuno-deficiency virus (HIV) among key populations in the selected hotspot towns of Ethiopia.

methodsWe undertook a cross-sectional implementation research during August 2017-January 2018. Trained TB focal persons and health extension workers (HEWs) identified female sex workers (FSWs), health care workers (HCWs), prison inmates, homeless, internally displaced people (IDPs), internal migratory workers (IMWs) and residents in missionary charities as key and vulnerable popuaiton. They carried out health education on the importance of TB screening and HIV testing prior to recruitment of the study participants. Symptomatic TB screening and HIV testing was done. The yield of TB was computed per 100,000 background key population.

resultsA total of 1878 vulnerable people were screened, out of which 726 (38.7%) presumptive TB cases and 87 (4.6%) TB cases were identified. The yield of TB was 1519 (95% CI: 1218.1-1869.9). The highest proportion (19.5%) and yield of TB case (6,286 (95% CI: 3980.8-9362.3)) was among HCWs. The prevalence of HIV infection was 6%, 67 out of 1,111 tested. IMWs and FSWs represented 49.3% (33) and 28.4% (13) of the HIV infections, respectively. There was a statistically significant association of active TB cases with previous history of TB (Adjusted Odds Ratio (AOR): 11 95% CI, 4.06-29.81), HIV infection (AOR: 7.7 95% CI, 2.24-26.40), and being a HCW (AOR: 2.42 95% CI, 1.09-5.34).

conclusionsThe prevalence of TB in key populations was nine times higher than 164/100,000 national estimated prevalence rate. The prevalence of HIV was five times higher than 1.15% of the national survey. The highest yield of TB was among the HCWs and the high HIV burden was detected among the FSWs and IMWs. These suggest a community and health facility based integrated and enhanced case finding approaches for TB and HIV in hotspot settings.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCross-Sectional StudiesEmigrants and ImmigrantsEthiopiaFemaleHealth EducationHealth PersonnelHIV-1HIV InfectionsHumansIll-Housed Persons

Identifiers

PMID32469997
PMCPMC7259557

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.