ArticlePloS one2020
Differentiating between spinal schwannomas and meningiomas using MRI: A focus on cystic change.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- Spinal Intradural Extramedullary Schwannomas Mimicking Intramedullary Tumors: A Case Series.Cureus · 2026Article
- A rare case of primary intradural spinal chordoma with a systematic review of the literature.Surgical neurology international · 2026Article
- Article
- Unmasking benign intradural-extramedullary spinal tumors: a systematic review on treatment outcomes and radiological features.Annals of medicine and surgery (2012) · 2025Article
- Pathology of the conus medullaris and cauda equina. Beyond the usual suspects.Insights into imaging · 2025Article
- A molecular array for 10-second diagnosis of common spinal tumor types with picosecond infrared laser mass spectrometry.Neuro-oncology · 2025Article
- Radiographic Features of Spinal Meningioma and Schwannoma: A Novel Specific Feature-Ginkgo Leaf Sign.Spine surgery and related research · 2025Article
- Totally Cystic Schwannoma in the Lumbar Spine: A Case Report.Advanced biomedical research · 2025Article
- Spinal schwannoma: Limitations of CT imaging.Radiology case reports · 2024Article
- Clinical, molecular, and genetic features of spinal meningiomas.Neuro-oncology advances · 2024Review
- Diagnostic and Therapeutic Insights into Spinal Glomangioma of a Unique Intradural, Extramedullary Presentation-Systematic Review.Diseases (Basel, Switzerland) · 2024Review
- Magnetic resonance imaging-based prediction models for differentiating intraspinal schwannomas from meningiomas: classification and regression tree and random forest analysis.Quantitative imaging in medicine and surgery · 2024Article
- Review
- A Workflow for Meaningful Interpretation of Classification Results from Handheld Ambient Mass Spectrometry Analysis Probes.International journal of molecular sciences · 2024Review
- Long-Term Functional Outcomes Following Surgical Treatment of Spinal Schwannomas: A Population-Based Cohort Study.Cancers · 2024Article
- Development of a novel prediction model for differential diagnosis between spinal myxopapillary ependymoma and schwannoma.Scientific reports · 2024Article
- Primary extracranial meningioma of the pelvis discovered on screening pelvic examination.BMJ case reports · 2023Article
- Automated Detection and Diagnosis of Spinal Schwannomas and Meningiomas Using Deep Learning and Magnetic Resonance Imaging.Journal of clinical medicine · 2023Article
- Review
- The value of quantitative magnetic resonance imaging signal intensity in distinguishing between spinal meningiomas and schwannomas.International journal of medical sciences · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo retrospectively determine the diagnostic ability of MRI in differentiating between intradural extramedullary spinal schwannomas and meningiomas.
methodsA total of 199 patients with spinal intradural extramedullary tumors who underwent preoperative contrast-enhanced MRI between January 2012 and December 2018 were included in this study. Two radiologists independently analyzed the presence of cystic change, dural tail sign, and neural foraminal extension. Clinical and MRI features between the two groups were compared by univariable and multivariable analyses using logistic regression. Interobserver agreements were calculated using kappa statistics.
resultsPatients with schwannoma showed significantly higher frequency of cystic change (96% vs 24%, P < 0.001), neural foraminal extension (29% vs 3%, P = 0.001), and lumbar location (41% vs 5%, P = 0.008). Patients with meningioma showed significantly higher frequency of dural tail sign (64% vs 1%, P < 0.001), thoracic location (75% vs 31%, P = 0.007), older age (59.7 years vs 47.6 years, P < 0.001), higher female predominance (83% vs 50%, P < 0.001), and smaller size (19.8 cm vs 28.8 cm, P < 0.001). Multivariable analysis showed that cystic change (P < 0.001; odds ratio [OR], 0.02), dural tail sign (P < 0.001; OR, 36.23), age (P = 0.032; OR, 1.06), and lumbar location (P = 0.006; OR, 0.02) were independent factors. Interobserver agreements were almost perfect for all analyses.
conclusionsMRI features were useful in differentiating between intradural extramedullary schwannomas from meningiomas. The presence of cystic change and dural tail sign were independently significant discriminators.
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