ArticleJournal of affective disorders2020
The Effect of Traumatic Events on the Longitudinal Course and Outcomes of Youth with Bipolar Disorder.
Article in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Seasonal mood variation in youth and young adults with bipolar spectrum disorder: A longitudinal prospective analysis.Journal of affective disorders · 2025Article
- The Types of Psychosocial Factors Associated with Suicidality Outcomes for People Living with Bipolar Disorder: A Scoping Review.International journal of environmental research and public health · 2024Article
- Childhood Trauma as an Environmental Determinant of Risk of Violence in Bipolar Disorder.Noro psikiyatri arsivi · 2023Article
- White Matter Correlates of Early-Onset Bipolar Illness and Predictors of One-Year Recurrence of Depression in Adults with Bipolar Disorder.Journal of clinical medicine · 2022Article
- Risk factors preceding new onset abuse among youth with bipolar disorder: A longitudinal prospective analysis.Journal of affective disorders · 2022Article
- Social and environmental variables as predictors of mania: a review of longitudinal research findings.Discover mental health · 2022Review
- Article
- What Do We Know about the Long-Term Course of Early Onset Bipolar Disorder? A Review of the Current Evidence.Brain sciences · 2021Review
- Longitudinal course of depressive symptom severity among youths with bipolar disorders: Moderating influences of sustained attention and history of child maltreatment.Journal of affective disorders · 2021Article
- Can Physical and/or Sexual Abuse Play a Role in the Female Choice of a Partner? A Cross-Sectional, Correlational Pilot Study.International journal of environmental research and public health · 2020Article
- The Impact of Childhood Trauma on Developing Bipolar Disorder: Current Understanding and Ensuring Continued Progress.Neuropsychiatric disease and treatment · 2020Review
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
backgroundExposure to severe Traumatic Events (TEs) has been associated with poor course and outcomes among individuals with Bipolar Disorder (BD). However, there is limited research on TEs among youth with BD, and few studies are longitudinal. This study prospectively followed a large sample of BD youth, examining the associations of lifetime TEs with their mood and functioning.
methodsBD participants (n=375; mean age=17; range 8-25y) were assessed, on average, every 7 months for a median 8.7 years. Psychopathology and lifetime trauma history were prospectively evaluated using the Longitudinal Interval Follow-Up Evaluation, and a traumatic events screening.
resultsAccounting for covariates, participants with one or more lifetime TEs (84%) showed earlier BD onset, poorer psychosocial functioning, worse mood symptoms, and more suicidal ideation, comorbidities, and family psychopathology than those without TEs. TEs during recovery periods increased recurrence risk (p<0.02). More TEs were associated with poorer mood course, particularly among victims of violence/abuse (p<0.02). Abused participants (34% physical; 17% sexual) showed earlier onset of substance use disorders, more suicidality and comorbidities compared to those without abuse. Comparisons of mood course before and after abuse occurred, and with participants without abuse, showed worsening mood symptoms after, specifically hypo/mania (p<0.03). LIMITATIONS: Prospective data was gathered longitudinally but assessed retrospectively at every follow-up; given approximate dates causality cannot be inferred; TEs severity was not assessed.
conclusionsSevere TEs, particularly abuse, were associated with poorer course and outcomes among BD youth. Prompt screening of trauma and early intervention may be warranted to minimize TEs impact.
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