Evidence map›Paper›PMID 32468897›Full record

ReviewJournal of the American Heart Association2020

Clinical Characteristics and Management of Methamphetamine-Associated Cardiomyopathy: State-of-the-Art Review.

Pavan K V Reddy, Tien M H Ng, Esther E Oh, Gassan Moady, Uri Elkayam

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07211724 (Methamphetamine Use Disorder Support in Heart Failure), which is not on this map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07211724 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Methamphetamine Use Disorder Support in Heart Failure (Meth HF) Pilot Study

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2026 to 2027Enrolled50ConditionsHeart Failure, Methamphetamine Use DisorderArmsMUD Management (contingency management +/- adjunctive MUD pharmacotherapy), HF GDMT management
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Modeling the Societal Impact of Methamphetamine-Associated Heart Failure.Journal of the American Heart Association · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Amphetamine-induced Reverse Takotsubo Cardiomyopathy and Thrombosis: A Case Report.Clinical practice and cases in emergency medicine · 2026
    Article
  13. Article
  14. Review
  15. Mechanisms underlying methamphetamine-induced disruption of testicular integrity.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pavan K V ReddyDivision of Cardiovascular Medicine Keck School of Medicine University of Southern California Los Angeles CA.
Tien M H NgSchool of Pharmacy University of Southern California Los Angeles CA.
Esther E OhSchool of Pharmacy University of Southern California Los Angeles CA.
Gassan MoadyDivision of Cardiovascular Medicine Keck School of Medicine University of Southern California Los Angeles CA.
Uri ElkayamDivision of Cardiovascular Medicine Keck School of Medicine University of Southern California Los Angeles CA.
University of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methamphetamine-associated cardiomyopathy (MACM) is an increasingly recognized disease entity in the context of a rapidly spreading methamphetamine epidemic. MACM may afflict individuals with a wide range of ages and socioeconomic backgrounds. Presentations can vary greatly and may involve several complications unique to the disease. Given the public health significance of this disease, there is a relative dearth of consensus material to guide clinicians in understanding, diagnosing, and managing MACM. This review therefore aims to: (1) describe pathologic mechanisms of methamphetamine as they pertain to the development, progression, and prognosis of MACM, and the potential to recover cardiac function; (2) summarize existing data from epidemiologic studies and case series in an effort to improve recognition and diagnosis of the disease; (3) guide short- and long-term management of MACM with special attention to expected or potential sequelae of the disease; and (4) highlight pivotal unanswered questions in need of urgent investigation from a public health perspective.

Indexed as

Amphetamine-Related DisordersAnimalsCardiomyopathiesCentral Nervous System StimulantsHeartHumansMethamphetaminePredictive Value of TestsRecovery of FunctionRisk FactorsTreatment OutcomeCentral Nervous System StimulantsMethamphetaminecardiomyopathydiagnosisheart failuremanagementmethamphetamine

Identifiers

PMID32468897
PMCPMC7428977
OpenAlexW3032165534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.