Evidence map›Paper›PMID 32468435›Full record

ArticleProbiotics and antimicrobial proteins2021

Hepatoprotective Effect of Probiotic Lactic Acid Bacteria on Thioacetamide-Induced Liver Fibrosis in Rats.

Chittapon Jantararussamee, Siripa Rodniem, Malai Taweechotipatr, Udomsri Showpittapornchai, Wisuit Pradidarcheep

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Review
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  5. Microbiota composition and intestinal barrier function modulated by tamsulosin andFrontiers in cellular and infection microbiology · 2025
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  6. Potential Protective Effect of Selenium-EnrichedJournal of microbiology and biotechnology · 2024
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  10. Heliyon · 2023
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  13. Review
  14. Article
  15. Antioxidants (Basel, Switzerland) · 2022
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. TheMicroorganisms · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chittapon JantararussameeDepartment of Anatomy, Faculty of Medicine, Srinakharinwirot University, Sukhumvit 23 Rd, Bangkok, 10110, Thailand.
Siripa RodniemDepartment of Anatomy, Faculty of Medicine, Srinakharinwirot University, Sukhumvit 23 Rd, Bangkok, 10110, Thailand.
Malai TaweechotipatrDepartment of Microbiology, Faculty of Medicine, Srinakharinwirot University, Sukhumvit 23 Rd, Bangkok, 10110, Thailand.
Udomsri ShowpittapornchaiDepartment of Anatomy, Faculty of Medicine, Srinakharinwirot University, Sukhumvit 23 Rd, Bangkok, 10110, Thailand.
Wisuit PradidarcheepDepartment of Anatomy, Faculty of Medicine, Srinakharinwirot University, Sukhumvit 23 Rd, Bangkok, 10110, Thailand. pthongp@gmail.com.
Srinakharinwirot University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic fibrosis is a reversible wound-healing response characterized by the accumulation of extracellular matrix. Probiotics have been used to prevent and treat various disorders. The aim of the present study was to investigate the hepatoprotective effects of probiotic lactic acid bacteria (mixture of Lactobacillus paracasei, Lactobacillus casei, and Weissella confusa) on thioacetamide (TAA)-induced liver fibrosis in rats. Thirty-five male Wistar rats were randomly divided into five groups: (1) control, (2) TAA, (3) TAA+probiotics, (4) TAA+silymarin, and (5) probiotics. Group 1 rats received a standard diet. In groups 2-4, fibrosis was induced by intraperitoneal injection of TAA (200 mg/kg BW) 3 times weekly for 8 consecutive weeks. Group 4 received TAA plus 100 mg/kg BW of silymarin 2 times weekly. Groups 3 and 5 were fed 10

Indexed as

LactobacillalesLiver CirrhosisAnimalsMaleRatsRats, WistarThioacetamideThioacetamideCollagen fiberHepatic stellate cellLactobacillus caseiLactobacillus paracaseiLiver inflammationWeissella confusa

Identifiers

PMID32468435
OpenAlexW3029751557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.