Evidence map›Paper›PMID 32468208›Full record

ArticleMikrochimica acta2020

An aptasensor strip-based colorimetric determination method for kanamycin using cellulose acetate nanofibers decorated DNA-gold nanoparticle bioconjugates.

Mohammed Awad Abedalwafa, Zhimin Tang, Yansha Qiao, Qianqian Mei, Gang Yang, Yan Li, Lu Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Aptamers used for biosensors and targeted therapy.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
    Pooled it
  2. Review
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  5. Article
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  9. Article
  10. Electrospun Nanofibers for Sensing and Biosensing Applications-A Review.International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Mohammed Awad AbedalwafaKey Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China.ORCID 0000-0003-2652-8172
Zhimin TangKey Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China.
Yansha QiaoKey Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China.
Qianqian MeiKey Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China.
Gang YangKey Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China.
Yan LiKey Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China. yanli@dhu.edu.cn.ORCID 0000-0002-9588-8991
Lu WangKey Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China. wanglu@dhu.edu.cn.
Donghua University · CN

Funding

111 Project "Biomedical Textile Materials Science and Technology B07024Fundamental Research Funds for the Central Universities 2232017D-03National Aerospace Science Foundation of China 51603034Seed Project of Key Laboratory of Textile Science and Technology of Ministry of Education KLTST201622
6 · The paper itself

Abstract

The preparation of portable colorimetric biosensor strips is described by combining aptamer-immobilized electrospun nanofiber membranes (A-NFMs) with signal probes (DNA-conjugated gold nanoparticles (AuNPs)) for determination of kanamycin (KMC) as a model analyte. The A-NFMs were decorated with complementary single-stranded DNA (cDNA) of KMC aptamer-conjugated AuNPs (cDNA@Au) to get the colorimetric biosensor strips. The constructed biosensor strips showed a significant absorbance decreasing band at 510 nm which induce a visual color change from pink to white when exposed to KMC, with a low detection limit of 2.5 nM (at S/N = 3). The effect is due to disassembling of cDNA@Au from NFMs in the presence of KMC because the aptamer has a higher affinity to KMC than its complementary DNA, which resulted in replacing cDNA@Au with KMC. Satisfactory performance was observed in real sample (drinking water and milk) analysis with a recovery of 98.9-102.2%. The constructed colorimetric biosensor test strips hold great application promise for food safety control. Graphical abstract Schematic representation of biosensor strips for kanamycin detection prepared with the cDNA@Au immobilized aptamer-based cellulose acetate nanofibers.

Indexed as

AnimalsAnti-Bacterial AgentsAptamers, NucleotideBiosensing TechniquesCelluloseColorimetryDNA, ComplementaryDrinking WaterFood ContaminationGoldKanamycinLimit of DetectionMetal NanoparticlesMilkNanofibersNucleic Acid HybridizationacetylcelluloseAnti-Bacterial AgentsAptamers, NucleotideCelluloseDNA, ComplementaryDrinking WaterGoldKanamycinWater Pollutants, ChemicalAntibiotic residueAptamerColorimetric assayElectrospun nanofiber membraneSignal probes

Identifiers

PMID32468208
OpenAlexW3030847382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.