Evidence map›Paper›PMID 32467997›Full record

ReviewInternational journal of oncology2020

Artificial intelligence radiogenomics for advancing precision and effectiveness in oncologic care (Review).

Eleftherios Trivizakis, Georgios Z Papadakis, Ioannis Souglakos, Nikolaos Papanikolaou, Lefteris Koumakis, Demetrios A Spandidos, Aristidis Tsatsakis, Apostolos H Karantanas, Kostas Marias

Abstract readReview
In one paragraph

Review in International journal of oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eleftherios TrivizakisComputational Biomedicine Laboratory (CBML), Foundation for Research and Technology Hellas (FORTH), 70013 Heraklion, Greece.
Georgios Z PapadakisComputational Biomedicine Laboratory (CBML), Foundation for Research and Technology Hellas (FORTH), 70013 Heraklion, Greece.
Ioannis SouglakosLaboratory of Translational Oncology, Medical School, University of Crete, 71003 Heraklion, Greece.
Nikolaos PapanikolaouComputational Biomedicine Laboratory (CBML), Foundation for Research and Technology Hellas (FORTH), 70013 Heraklion, Greece.
Lefteris KoumakisComputational Biomedicine Laboratory (CBML), Foundation for Research and Technology Hellas (FORTH), 70013 Heraklion, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece.
Aristidis TsatsakisLaboratory of Forensic Sciences and Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Apostolos H KarantanasComputational Biomedicine Laboratory (CBML), Foundation for Research and Technology Hellas (FORTH), 70013 Heraklion, Greece.
Kostas MariasComputational Biomedicine Laboratory (CBML), Foundation for Research and Technology Hellas (FORTH), 70013 Heraklion, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The new era of artificial intelligence (AI) has introduced revolutionary data‑driven analysis paradigms that have led to significant advancements in information processing techniques in the context of clinical decision‑support systems. These advances have created unprecedented momentum in computational medical imaging applications and have given rise to new precision medicine research areas. Radiogenomics is a novel research field focusing on establishing associations between radiological features and genomic or molecular expression in order to shed light on the underlying disease mechanisms and enhance diagnostic procedures towards personalized medicine. The aim of the current review was to elucidate recent advances in radiogenomics research, focusing on deep learning with emphasis on radiology and oncology applications. The main deep learning radiogenomics architectures, together with the clinical questions addressed, and the achieved genetic or molecular correlations are presented, while a performance comparison of the proposed methodologies is conducted. Finally, current limitations, potentially understudied topics and future research directions are discussed.

Indexed as

Artificial IntelligenceImaging GenomicsPrecision MedicineRadiation OncologyBiomarkers, TumorDecision Support Systems, ClinicalDeep LearningHumansImage Processing, Computer-AssistedNeoplasmsBiomarkers, Tumorartificial intelligencedeep learningmachine learningmedical imaging/radiogenomicsoncologyprecision medicine

Identifiers

PMID32467997
PMCPMC7252460

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.