Evidence map›Paper›PMID 32467350›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2020

Colorectal Neoplasia among Patients with and without Human Immunodeficiency Virus.

Adil Faqih, Amit G Singal, Hannah M Fullington, Benjamin Hewitt, Ezra Burstein, Purva Gopal, Annika Wylie, John Abrams, Caitlin C Murphy

Open access · greenAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Adil FaqihDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0003-4737-3085
Amit G SingalDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Hannah M FullingtonDepartment of Population & Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Benjamin HewittDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Ezra BursteinDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0003-4341-6367
Purva GopalHarold C. Simmons Comprehensive Cancer Center, Dallas, Texas.
Annika WylieDepartment of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas.
John AbramsHarold C. Simmons Comprehensive Cancer Center, Dallas, Texas.
Caitlin C MurphyDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas. caitlin.murphy@utsouthwestern.edu.
Texas Oncology · USThe University of Texas Southwestern Medical Center · US

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Sandi Leigh Pruitt · 2010 to 2026
$53.7M
Cancer Biology Training GrantT32CA124334 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAY, JERRY WILLIAM · 2007 to 2021
$5.3M
Suppression of mobile elements by p53 genesR01GM115682 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ABRAMS, JOHN M · 2015 to 2024
$2.7M
Tumor suppression, p53 and retrotransposonsR01CA222579 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI ABRAMS, JOHN M · 2018 to 2022
$1.8M
NCI NIH HHS P30 CA142543NCI NIH HHS R01 CA222579NCI NIH HHS T32 CA124334NIGMS NIH HHS R01 GM115682
6 · The paper itself

Abstract

backgroundIncreasing availability of highly active antiretroviral therapy (HAART) for human immunodeficiency virus (HIV) has led to prolonged survival and rising incidence of non-HIV-defining cancers among patients with HIV. Compared with the general population, risk of colorectal cancer may differ among those with HIV due to immunosuppression, oncogenic viral coinfections, and higher prevalence of risk factors.

methodsWe identified patients (age ≥50 years) diagnosed with HIV, prescribed HAART for ≥6 months, and receiving care in two large health care systems in Dallas, TX. Patients received a first colonoscopy between January 2009 and December 2017. We calculated a standardized prevalence ratio as the ratio of observed to expected number of advanced neoplasia (high-risk adenoma or colorectal cancer) using an age- and sex-matched cohort of patients without HIV (

resultsAmong patients with HIV (

conclusionsThere was no difference in the prevalence of colorectal neoplasia between patients with and without HIV. IMPACT: Patients with HIV appear to have similar risk of colorectal neoplasia compared to those without HIV and can therefore follow average-risk colorectal cancer screening guidelines.

Indexed as

Colorectal NeoplasmsFemaleHIV InfectionsHumansMaleMiddle AgedRisk Factors

Identifiers

PMID32467350
PMCPMC7415639
OpenAlexW3030369855

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.