Evidence map›Paper›PMID 32467294›Full record

ReviewDevelopment (Cambridge, England)2020

The extracellular matrix in development.

David A Cruz Walma, Kenneth M Yamada

Open access · hybridAbstract readReview
In one paragraph

Review in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 210 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
210citing papers in PubMed, 1 pooled it
22.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

210 citing papers in PubMed, 1 synthesis or guideline pooled it, 397 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  10. Review
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  14. Extracellular matrix chemistry tunes bacterial biofilm metabolism and optimizes fitness.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  15. Article
  16. Article
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  19. Article
  20. Article

150 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David A Cruz WalmaCell Biology Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, 20892-4370, USA kenneth.yamada@nih.gov david.cruzwalma@nih.gov.
Kenneth M YamadaCell Biology Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, 20892-4370, USA kenneth.yamada@nih.gov david.cruzwalma@nih.gov.ORCID 0000-0003-1512-6805
National Institutes of Health · US

Funding

Craniofacial Developmental DynamicsZIADE000525 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI YAMADA, KENNETH · 2009 to 2025
$14.5M
Cell-Surface Interactions in PathogenesisZIADE000719 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI YAMADA, KENNETH · 2009 to 2025
$13.5M
Cell-Matrix Interactions and MigrationZIADE000524 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI YAMADA, KENNETH · 2009 to 2025
$10.2M
Matrix Organization and DimensionalityZIADE000718 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI YAMADA, KENNETH · 2009 to 2025
$8.9M
6 · The paper itself

Abstract

As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides both physical support and signaling regulation to cells. Some ECM molecules provide a fibrillar environment around cells, while others provide a sheet-like basement membrane scaffold beneath epithelial cells. In this Review, we focus on recent studies investigating the mechanical, biophysical and signaling cues provided to developing tissues by different types of ECM in a variety of developing organisms. In addition, we discuss how the ECM helps to regulate tissue morphology during embryonic development by governing key elements of cell shape, adhesion, migration and differentiation.

Indexed as

AnimalsBasement MembraneCell AdhesionCell DifferentiationCell MovementCell PolarityCell ShapeEmbryonic DevelopmentExtracellular MatrixFemaleHumansPregnancySignal TransductionAdhesionBiophysicalDifferentiationEmbryoExtracellular matrixMigration

Identifiers

PMID32467294
PMCPMC7272360
OpenAlexW3029750330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.