Evidence map›Paper›PMID 32467231›Full record

ArticleThe Journal of biological chemistry2020

An aberrantly sustained emergency granulopoiesis response accelerates postchemotherapy relapse in

Hao Wang, Chirag A Shah, Liping Hu, Weiqi Huang, Leonidas C Platanias, Elizabeth A Eklund

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Hao WangDepartment of Medicine, Northwestern University, Chicago, Illinois, USA.
Chirag A ShahDepartment of Medicine, Northwestern University, Chicago, Illinois, USA.
Liping HuDepartment of Medicine, Northwestern University, Chicago, Illinois, USA.
Weiqi HuangDepartment of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-6779-6961
Leonidas C PlataniasDepartment of Medicine, Northwestern University, Chicago, Illinois, USA.
Elizabeth A EklundDepartment of Medicine, Northwestern University, Chicago, Illinois, USA e-eklund@northwestern.edu.
Northwestern University · US

Funding

Triad1 regulates myelopoiesis and functions as a leukemia suppressorR01CA195642 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI EKLUND, ELIZABETH ANN · 2015 to 2019
$1.8M
Molecular mechanisms for bone marrow failure and clonal progression during the innate immune response in Fanconi AnemiaR01DK121354 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI EKLUND, ELIZABETH ANN · 2019 to 2022
$1.4M
Molecular mechanisms of drug resistance and disease progression in acute myeloid leukemia.I01BX004635 · VA · JESSE BROWN VA MEDICAL CENTER · PI EKLUND, ELIZABETH ANN · 2019 to 2025
–
BLRD VA I01 BX004635NCI NIH HHS R01 CA195642NIDDK NIH HHS R01 DK121354
6 · The paper itself

Abstract

Acute myeloid leukemia (AML) with mixed lineage leukemia 1 (

Indexed as

Gene RearrangementLeukopoiesisAnimalsErbB ReceptorsHistone-Lysine N-MethyltransferaseHumansLeukemia, Myeloid, AcuteMiceMyeloid-Lymphoid Leukemia ProteinNeoplasms, ExperimentalNeoplastic Stem CellsRecurrenceSignal TransductionUbiquitin-Protein LigasesArih2 protein, mouseErbB ReceptorsHistone-Lysine N-MethyltransferaseKmt2a protein, mouseMyeloid-Lymphoid Leukemia ProteinUbiquitin-Protein Ligasescancer chemotherapyE3 ubiquitin ligaseemergency granulopoiesisgene regulationinnate immunitykinase signalingleukemiamixed lineage leukemia (MLL)receptor tyrosine kinase (RTK)TRIAD1ubiquitin ligase

Identifiers

PMID32467231
PMCPMC7363149
OpenAlexW3030368986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.