SynthesisBMC oral health2020
Conscious sedation for the management of dental anxiety in third molar extraction surgery: a systematic review.
Synthesis in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Sedative and adverse effect comparison between oral midazolam and nitrous oxide inhalation in tooth extraction: a meta-analysis.BMC oral health · 2023Pooled it
- Comparison of remimazolam and dexmedetomidine for conscious sedation in elderly patients undergoing dental implant surgery: a prospective randomized controlled trial.BMC geriatrics · 2025Trial
- Immediate postoperative anesthesia with either lidocaine or bupivacaine: A short-term clinical response.Journal of periodontology · 2025Trial
- A Comparison of the Effect of Remimazolam and Midazolam on Recovery and Preserved Memory Function for Patients with Dental Extraction Anxiety.Drug design, development and therapy · 2025Trial
- Non-Pharmacological Interventions for Managing Preoperative Anxiety in the Context of Odontectomy: A Systematic Review.Dentistry journal · 2026Review
- The median effective dose (EDBMC anesthesiology · 2026Article
- Autonomic cardiovascular mechanisms linked to stress in dental practice.British dental journal · 2026Review
- Article
- Internet-Based Cognitive Behavioral Therapy for Children and Adolescents With Dental or Injection Phobia: 1-year Follow-Up Assessment.JMIR pediatrics and parenting · 2025Article
- Evaluation of dental treatments under nitrous oxide-oxygen inhalation sedation in pediatric patients with dental anxiety: a 10-Year retrospective study.BMC oral health · 2025Article
- Review
- Evaluation of the effect of dental anxiety on vital signs in the order of third molar extraction.BMC oral health · 2024Article
- Prevalence and Factors Influencing Post-Operative Complications following Tooth Extraction: A Narrative Review.International journal of dentistry · 2024Review
- Article
- A comparative study of patient satisfaction about anesthesia with dexmedetomidine for ambulatory dental surgery.BMC research notes · 2022Article
- Analysis of changes and trends in the use of sedatives in dental sedation using data from the National Health Insurance in Korea.Journal of dental anesthesia and pain medicine · 2022Article
- Estimating the Need for Sedation in Patients with Dental Anxiety and Medical Complexities Reporting to Tertiary Care Dental Hospital Using the IOSN Tool.International journal of dentistry · 2022Article
- Kinesiology Taping as an Innovative Measure against Post-Operative Complications after Third Molar Extraction-Systematic Review.Journal of clinical medicine · 2020Review
- Vietnamese Validation of the Index of Dental Anxiety and Fear: A Cross-sectional Study.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDental anxiety is a condition associated with avoidance of dental treatment and increased medical and surgical risks. This systematic review aims to summarize available evidence on conscious sedation techniques used for the management of Dental anxiety in patients scheduled for third molar extraction surgery, to identify best approaches and knowledge gaps.
methodsA comprehensive search was conducted including MEDLINE/Pubmed, EMBASE, SCOPUS, clinicaltrials.gov and the Cochrane Database of Systematic Reviews through March 2019. Only randomized controlled trials were included. PRISMA guidelines were followed. Risk of bias was appraised as reported in the Cochrane Handbook for Systematic Reviews of Interventions.
resultsSeventeen RCTs with a total of 1788 patients were included. Some aspects limited the feasibility of a meaningful meta-analysis, thus a narrative synthesis was conducted. Conscious sedation was associated with improvement in Dental anxiety in six studies. One study reported lower cortisol levels with midazolam vs. placebo, while another study found significant variation in perioperative renin levels with remifentanil vs. placebo.
conclusionsThis review found inconclusive and conflicting findings about the role of Conscious sedation in managing Dental anxiety during third molar extraction surgery. Relevant questions remain unanswered due to the lack of consistent, standardized outcome measures. Future research may benefit from addressing these limitations in study design.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.