Evidence map›Paper›PMID 32466661›Full record

ReviewCritical reviews in biochemistry and molecular biology2020

Retinol-binding protein 2 (RBP2): biology and pathobiology.

William S Blaner, Pierre-Jacques Brun, Rossana M Calderon, Marcin Golczak

Open access · greenAbstract readReview
In one paragraph

Review in Critical reviews in biochemistry and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  14. Frontiers in genetics · 2023
    Article
  15. Article
  16. Article
  17. Retinol-binding protein 2 (RBP2): More than just dietary retinoid uptake.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2022
    Review
  18. Article
  19. Observational
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

William S BlanerDepartment of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA.ORCID 0000-0002-9847-7506
Pierre-Jacques BrunDepartment of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Rossana M CalderonDepartment of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Marcin GolczakDepartment of Pharmacology and Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, OH, USA.
Columbia University · USCase Western Reserve University · US

Funding

POSTDOCTORAL TRAINING IN ARTERIOSCLEROSIS RESEARCHT32HL007343 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HENRY N GINSBERG, Muredach P Reilly · 1985 to 2026
$12.7M
Postprandial Vitamin AR01DK068437 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANER, WILLIAM S · 2004 to 2023
$7.0M
RBP2 Biology and PathobiologyR01DK122071 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WILLIAM S BLANER, Marcin Bernard Golczak · 2019 to 2026
$4.6M
Regulation of vitamin A metabolism in the eyeR01EY023948 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI GOLCZAK, MARCIN BERNARD · 2014 to 2023
$3.8M
Vitamin A Homeostasis: Retinyl Ester StoresR01DK101251 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANER, WILLIAM S, HARRISON, EARL HOWARD · 2016 to 2018
$1.4M
Alcohol, Retinoids and Pancreas BiologyR21AA028110 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANER, WILLIAM S · 2019 to 2020
$425k
NEI NIH HHS R01 EY023948NHLBI NIH HHS T32 HL007343NIAAA NIH HHS R21 AA028110NIDDK NIH HHS R01 DK068437NIDDK NIH HHS R01 DK101251NIDDK NIH HHS R01 DK122071
6 · The paper itself

Abstract

Retinol-binding protein 2 (RBP2; originally cellular retinol-binding protein, type II (CRBPII)) is a 16 kDa cytosolic protein that in the adult is localized predominantly to absorptive cells of the proximal small intestine. It is well established that RBP2 plays a central role in facilitating uptake of dietary retinoid, retinoid metabolism in enterocytes, and retinoid actions locally within the intestine. Studies of mice lacking

Indexed as

AdultAnimalsEmbryonic DevelopmentFemaleHumansImmunity, InnateIntestine, SmallLiverMaleMonoglyceridesObesityPregnancyRetinoidsRetinol-Binding Proteins, CellularVitamin AMonoglyceridesRetinoidsRetinol-Binding Proteins, CellularVitamin Aendocannabinoidenteroendocrine signalingglucose-dependent insulinotropic polypeptide (GIP) and dietary fatintestinemonoacylglycerolobesityretinoidVitamin A

Identifiers

PMID32466661
PMCPMC7593873
OpenAlexW3032535236

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.