Evidence map›Paper›PMID 32466624›Full record

ArticleMarine drugs2020

Effects of a Newly Developed Enzyme-Assisted Extraction Method on the Biological Activities of Fucoidans in Ocular Cells.

Philipp Dörschmann, Maria Dalgaard Mikkelsen, Thuan Nguyen Thi, Johann Roider, Anne S Meyer, Alexa Klettner

Abstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Comparison of Fucoidans fromInternational journal of molecular sciences · 2023
    Article
  4. Article
  5. Interaction of High-Molecular Weight Fucoidan fromInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Philipp DörschmannDepartment of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.
Maria Dalgaard MikkelsenDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, 2800 Kgs. Lyngby, Denmark.
Thuan Nguyen ThiDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, 2800 Kgs. Lyngby, Denmark.
Johann RoiderDepartment of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.
Anne S MeyerDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, 2800 Kgs. Lyngby, Denmark.
Alexa KlettnerDepartment of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.

Funding

Innovation Fund Denmark 0603-00522BInterreg 39-1.0-16
6 · The paper itself

Abstract

Fucoidans from brown seaweeds are promising substances as potential drugs against age-related macular degeneration (AMD). The heterogeneity of fucoidans requires intensive research in order to find suitable species and extraction methods. Ten different fucoidan samples extracted enzymatically from

Indexed as

Cell SurvivalEyeHumansMacular DegenerationOphthalmic SolutionsPlant ExtractsPolysaccharidesProtective AgentsSeaweedfucoidanOphthalmic SolutionsPlant ExtractsPolysaccharidesProtective Agentsage-related macular degenerationenzymatic purificationfucoidanfucoseFucus distichus subsp. evanescensLaminaria digitataoxidative stressretinal pigment epitheliumSaccharina latissimaVEGF

Identifiers

PMID32466624
PMCPMC7344579

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.