Evidence map›Paper›PMID 32466598›Full record

ReviewNutrients2020

Metabolic Impacts of Confinement during the COVID-19 Pandemic Due to Modified Diet and Physical Activity Habits.

María Martinez-Ferran, Fernando de la Guía-Galipienso, Fabián Sanchis-Gomar, Helios Pareja-Galeano

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04501991 (Determining the Impact of COVID-19 Lockdown on Metabolic Control in Individuals With Type 2 Diabetes), which is not on this map. Cited by 191 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
191citing papers in PubMed, 2 pooled it
87.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04501991 completednot on this map

Determining the Impact of COVID-19 Lockdown on Metabolic Control in Individuals With Type 2 Diabetes

TypeobservationalSponsorUniversity of PisaRan2020 to 2020Enrolled114ConditionsType 2 Diabetes, Metabolic ControlArmsantidiabetic treatment
3 · Its place in the literature

Who cites it

191 citing papers in PubMed, 2 syntheses or guidelines pooled it, 376 citations in OpenAlex.

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  15. Causal association between PMScientific reports · 2025
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131 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

María Martinez-FerranFaculty of Sports Sciences and Physiotherapy, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Madrid, Spain.
Fernando de la Guía-GalipiensoCardiology Service, Hospital Clínica Benidorm, 03501 Benidorm, Alicante, Spain.
Fabián Sanchis-GomarDepartment of Physiology, Faculty of Medicine, University of Valencia and INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.ORCID 0000-0003-0424-4208
Helios Pareja-GaleanoFaculty of Sports Sciences and Physiotherapy, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Madrid, Spain.ORCID 0000-0002-5780-2712
Universidad Europea de Madrid · ESHospital Clínica Benidorm · ESUniversitat de València · ES

Funding

Universidad Europea de Madrid #2019/UEM01
6 · The paper itself

Abstract

While the detrimental effects of a chronic positive energy balance due to a sedentary lifestyle have been well established, the impacts of a short period of abruptly reduced physical activity and overeating arising from strict confinement due to the COVID-19 pandemic will soon start to emerge. To reasonably anticipate major consequences according to the available evidence, we hereby review the literature for studies that have explored the health impacts of several weeks of a reduction in physical activity and daily step-count combined with modified eating habits. These studies identify as main metabolic consequences increases in insulin resistance, total body fat, abdominal fat and inflammatory cytokines. All these factors have been strongly associated with the development of metabolic syndrome, which in turn increases the risk of multiple chronic diseases. A plausible mechanism involved in these impacts could be a positive energy balance promoted by maintaining usual dietary intake while reducing energy expenditure. This means that just as calorie intake restriction could help mitigate the deleterious impacts of a bout of physical inactivity, overeating under conditions of home confinement is very likely to exacerbate these consequences. Moreover, hypertension, diabetes, and cardiovascular disease have been identified as potential risk factors for more severely ill patients with COVID-19. Thus, adequate control of metabolic disorders could be important to reduce the risk of severe COVID-19.

Indexed as

QuarantineSedentary BehaviorBetacoronavirusConfined SpacesCoronavirus InfectionsCOVID-19DietEnergy IntakeEnergy MetabolismHumansInsulin ResistanceMetabolic SyndromePandemicsPneumonia, ViralRisk FactorsSARS-CoV-2acute sedentary lifestyleCOVID-19insulin resistancemetabolic consequencesmetabolic syndromepositive energy balancesarcopeniastep reduction

Identifiers

PMID32466598
PMCPMC7352228
OpenAlexW3031923119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.