Evidence map›Paper›PMID 32466595›Full record

ReviewCancers2020

PSMA Theranostics: Review of the Current Status of PSMA-Targeted Imaging and Radioligand Therapy.

Wallace Jones, Kelly Griffiths, Pedro C Barata, Channing J Paller

Abstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. AnCurrent radiopharmaceuticals · 2024
    Trial
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Development of Prostate-Specific Lysosome-Targeting Degraders.Journal of the American Chemical Society · 2026
    Article
  15. Article
  16. Article
  17. Clinical Characteristics Associated with High [Nuclear medicine and molecular imaging · 2026
    Article
  18. Review
  19. Review
  20. Preclinical Evaluation of a Novel PSMA-Targeted AgentTomography (Ann Arbor, Mich.) · 2025
    Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wallace JonesDepartment of Internal Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Kelly GriffithsJohns Hopkins University, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21231 USA.
Pedro C BarataDepartment of Hematology-Oncology, Tulane University School of Medicine, New Orleans, LA 70112; USA.
Channing J PallerJohns Hopkins University, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21231 USA.ORCID 0000-0003-3658-1858

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI JUDD E SHELLITO · 2012 to 2026
$69.1M
NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Prostate-specific membrane antigen (PSMA) has been the subject of extensive investigation in the past two decades as a promising molecular target for prostate cancer (PCa). Its appealing molecular features have enabled the development of a novel diagnostic and therapeutic-thus "theranostic"-approach to PCa. There is now substantial evidence of the high sensitivity of PSMA-targeted imaging for PCa lesions and growing evidence of the therapeutic efficacy of PSMA radioligand therapy for metastatic castration-resistant prostate cancer. This article presents a broad overview of the current status of PSMA theranostics, including current evidence, potential clinical impact, and active areas of research.

Indexed as

prostate cancerprostate specific membrane antigentheranostics

Identifiers

PMID32466595
PMCPMC7352725

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.